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    • Gene expression profiling of C. elegans under various thermal conditions

    Metadata Updated: April 24, 2025

    To realistically evaluate the effects of the environment in space it is necessary to understand the effects of external factors during sample transport from Earth to space. The present study focused on temperature profiling the altered gene expression that develops under low cultivation temperatures in C. elegans used as a space life science model. The 7903 genes were selected as differentially expressed genes and divided into five sets with similar expression patterns using k-means clustering. Results from Gene Ontology analysis are significantly indicated that the cell cycle related genes and the TGF?/insulin-like signal pathway related genes changed. The TGF?/insulin-like signal pathway is expected to be activated due to low temperatures as well as by other stressors. To determine the genes whose expression changed four thermal conditions (10 15 20 and 25 xa1C) DNA microarray analysis was performed. The data consisted of 12 samples consisting of three biological replicates at each temperature.

    Access & Use Information

    Public: This dataset is intended for public access and use. License: No license information was provided. If this work was prepared by an officer or employee of the United States government as part of that person's official duties it is considered a U.S. Government Work.

    Downloads & Resources

    Dates

    Metadata Created Date January 31, 2023
    Metadata Updated Date April 24, 2025
    Data Update Frequency irregular

    Metadata Source

    Harvested from NASA Data.json

    Other Data Resources

    Additional Metadata

    Resource Type Dataset
    Metadata Created Date January 31, 2023
    Metadata Updated Date April 24, 2025
    Publisher National Aeronautics and Space Administration
    Maintainer
    Identifier nasa_genelab_GLDS-40_sebd-hw92
    Data First Published 2018-06-26
    Data Last Modified 2025-04-23
    Category Earth Science
    Public Access Level public
    Data Update Frequency irregular
    Bureau Code 026:00
    Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
    Schema Version https://project-open-data.cio.gov/v1.1/schema
    Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
    Harvest Object Id 3699c85b-83a3-4d0d-a5d3-03cf7cda9329
    Harvest Source Id 58f92550-7a01-4f00-b1b2-8dc953bd598f
    Harvest Source Title NASA Data.json
    Homepage URL https://data.nasa.gov/dataset/gene-expression-profiling-of-c-elegans-under-various-thermal-conditions
    Program Code 026:005
    Source Datajson Identifier True
    Source Hash 8972e0e4c7b5d57b93dd2093a8364fde25f6d278d0c78254bd6ee00de89afb7d
    Source Schema Version 1.1

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