60 datasets found
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Federal
Transcription profiling of mouse osteoblasts under static vs simulated microgravity
National Aeronautics and Space Administration —
The below table includes a smaller list of data that was analyzed by dChip and filtered by pvalue such that a file with about 4600 genes was obtained which allowed... -
Federal
Radiation responses in peripheral white blood cells of smokers and non-smokers
National Aeronautics and Space Administration —
Understanding the possible impact of potential confounding factors is necessary for any approach to radiation biodosimetry. Potential confounding factors have not... -
Federal
Effect of simulated microgravity on E. coli K12 MG1655 growth and gene expression
National Aeronautics and Space Administration —
This study demonstrates simulated microgravity effects on E. coli K 12 MG1655 when grown on LB medium supplemented with glycerol. The results imply that E. coli... -
Federal
Genechip analysis of bone marrow osteoprogenitors exposed to microgravity
National Aeronautics and Space Administration —
In March 2006 murine Bone Marrow Stromal Cells (BMSC) were flown in the Soyuz 12S to the International Space Station to investigate the effects of microgravity on... -
Federal
IMR90 bystander experiment 0.5 Gy alpha particle
National Aeronautics and Space Administration —
The existence of a radiation bystander effect in which non-irradiated cells respond to signals from irradiated cells is well established. It raises concerns for the... -
Federal
Expression data from SPHINX (SPaceflight of Huvec: an INtegrated eXperiment)
National Aeronautics and Space Administration —
Changes in the physical environment modulate cell responses and may lead to the impairment or even failure of tissue function as a result of mechanotransduction... -
Federal
Expression Data from International C.elegans Experiment 1st
National Aeronautics and Space Administration —
The effect of microgravity on gene expression in C.elegans was comprehensively analysed by DNA microarray. This is the first DNA microarray analysis for C.elegans... -
Federal
Low dose ionizing radiation treated lymphoblastoid cells
National Aeronautics and Space Administration —
Irradiated cell lines exposed to 1-10 cGy 2 Lymphoblastoid cell lines (GM15510 and GM15036) irradiated 1 2.5 5 7.5 10 cGy RNA is isolated and labeled using a T7... -
Federal
DNA copy number analysis from mice with radiation-induced acute myeloid leukemia
National Aeronautics and Space Administration —
Certain mouse strains such as CBA C3H and RFM have high incidence of radiation-induced acute myeloid leukemia (AML). The data in this series wer generated by using... -
Federal
Radiation responses in peripheral white blood cells of smokers and non-smokers
National Aeronautics and Space Administration —
Understanding the possible impact of potential confounding factors is necessary for any approach to radiation biodosimetry. Potential confounding factors have not... -
Federal
MESSAGE 2 space experiment with Rhodospirillum rubrum S1H
National Aeronautics and Space Administration —
R. rubrum S1H inoculated on solid agar rich media was sent to the ISS in October 2003 (MESSAGE-part 2 experiment). After 10 days flight R. rubrum cultures returned... -
Federal
Response of Pseudomonas aeruginosa PAO1 to low shear modeled microgravity
National Aeronautics and Space Administration —
Anticipating the risk for infectious disease during space exploration and habitation is a critical factor to ensure safety health and performance of the crewmembers.... -
Federal
Non-targeted effects of low dose ionizing radiation act via TGF-beta to promote mammary carcinogenesis
National Aeronautics and Space Administration —
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy) 1 and 4... -
Federal
IMR90 radiation bystander time-course experiment 0.5Gy alpha particle
National Aeronautics and Space Administration —
The radiation bystander effect is an important component of the overall biological response of tissues and organisms to ionizing radiation. Little is known about the... -
Federal
Low dose ionizing radiation treated lymphoblastoid cells
National Aeronautics and Space Administration —
Irradiated cell lines exposed to 1-10 Gy 2 Lymphoblastoid cell lines (GM15510 and GM15036) irradiated 1 2.5 5 7.5 10 Gy RNA is isolated and labeled using a T7... -
Federal
Microarray Profile of Gene Expression during Osteoclast Differentiation in Modeled Microgravity
National Aeronautics and Space Administration —
Microgravity leads to a 10-15% loss of bone mass in astronauts during space flight. Osteoclast is the multinucleated bone resorbing cell. In this study we used NASA... -
Federal
Global Identification of Noncoding RNAs in S. cerevisiae
National Aeronautics and Space Administration —
Genome-wide detection of novel non-coding RNAs in S. cerevisiae by modulating an RNase P pathway through the depletion of a component RPP1. Nearly 400,000 36-mer... -
Federal
Microgravity effect on C. elegans N2/VC (CERISE 8days)
National Aeronautics and Space Administration —
Microgravity effect on C. elegans gene expression was analysed by whole genome microarray. The worms were cultivated under microgravity for 8 days in the Japanese... -
Federal
MESSAGE 2 space experiment with Rhodospirillum rubrum S1H
National Aeronautics and Space Administration —
R. rubrum S1H inoculated on solid agar rich media was sent to the ISS in October 2003 (MESSAGE-part 2 experiment). After 10 days flight R. rubrum cultures returned... -
Federal
T Cell Activation in Microgravity Compared to 1g (Earth s) Gravity
National Aeronautics and Space Administration —
This study tested the hypothesis that transcription of immediate early genes is inhibited in T cells activated in microgravity (mg). Immunosuppression during...
60 datasets found