22 datasets found
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Federal
A Machine Learning Model to Estimate Toxicokinetic Half-Lives of Per- and Polyfluoro-Alkyl Substances (PFAS) in Multiple Species
U.S. Environmental Protection Agency —
Data and code for "Dawson, D.E.; Lau, C.; Pradeep, P.; Sayre, R.R.; Judson, R.S.; Tornero-Velez, R.; Wambaugh, J.F. A Machine Learning Model to Estimate Toxicokinetic... -
Federal
Analogue search results for p,p'-DDD
U.S. Environmental Protection Agency —
The dataset contains the outputs for the analogue searches conducted for the chemical of interest, p,p'-DDD. This dataset is associated with the following... -
Federal
ToxCast bioactivity data for p,p'-DDD and analogues
U.S. Environmental Protection Agency —
Bioactivity data for p,p'-DDD and analogues from ToxCast assays conducted in liver cells were sourced from the EPA’s CompTox Chemistry Dashboard. The links also... -
Federal
Bayesian inference of chemical exposures from NHANES urine biomonitoring data
U.S. Environmental Protection Agency —
Data and files for "Stanfield, Z., Setzer, R.W., Hull, V. et al. Bayesian inference of chemical exposures from NHANES urine biomonitoring data. J Expo Sci Environ... -
Federal
Development and Evaluation of a High Throughput Inhalation Model for Organic Chemicals
U.S. Environmental Protection Agency —
This investigation was broken down into three interrelated steps: data collection, model building, and model evaluation. R software (v. 3.5.1) with the httk package... -
Federal
Impact of gut permeability on estimation of oral bioavailability for chemicals in commerce and the environment
U.S. Environmental Protection Agency —
Supplementary files for "Impact of gut permeability on estimation of oral bioavailability for chemicals in commerce and the environment" -
Federal
Category-Based Toxicokinetic Evaluations of Data-Poor Per- and Polyfluoroalkyl Substances (PFAS) using Gas Chromatography Coupled with Mass Spectrometry
U.S. Environmental Protection Agency —
Supplementary material for "Kreutz, A.; Clifton, M.S.; Henderson, W.M.; Smeltz, M.G.; Phillips, M.; Wambaugh, J.F.; Wetmore, B.A. Category-Based Toxicokinetic... -
Federal
Model Code Associated with "Challenges for extrapolation of risk from ingestion to inhalation exposure for per- and polyfluorinated alkyl acids and their precursors"
U.S. Environmental Protection Agency —
This ScienceHub entry contains a zip file with the pharmacokinetic modeling code used for the linked publication, "Challenges for extrapolation of risk from ingestion... -
Federal
ToxCast bioactivity data and model predictions for the ER and AR pathways for p,p'-DDD and analogues
U.S. Environmental Protection Agency —
ToxCast bioactivity data and model predictions for the estrogen receptor (ER) and androgen receptor (AR) pathways were obtained from the inks provided. This dataset... -
Federal
Locomotor activity and tissues levels following acute administration of lambda- and gamma-cyhalothrin in rats
U.S. Environmental Protection Agency —
raw motor activity counts and tissue levels. This dataset is associated with the following publication: Moser, G., Z. Liu, C. Schlosser, T. Spanogle, A.... -
Federal
Saunders et al._Dietary bioaccumulation and biotransformation of hydrophobic organic sunscreen agents in rainbow trout
U.S. Environmental Protection Agency —
Organic ultraviolet filters (UVFs; also known as sunscreen agents) used in personal care and consumer products can enter the aquatic environment via wastewater... -
Federal
In Vitro Hepatic Clearance Evaluations of Per- and Polyfluoroalkyl Substances (PFAS) across Multiple Structural Categories
U.S. Environmental Protection Agency —
Dataset for "Crizer, D.M.; Rice, J.R.; Smeltz, M.G.; Lavrich, K.S.; Ravindra, K.; Wambaugh, J.F.; DeVito, M.; Wetmore, B.A. In Vitro Hepatic Clearance Evaluations of... -
Federal
HTTK R Package v1.4 - JSS Article on HTTK: R Package for High-Throughput Toxicokinetics
U.S. Environmental Protection Agency —
httk: High-Throughput Toxicokinetics Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") using data obtained from... -
Federal
HTTK R Package v1.0
U.S. Environmental Protection Agency —
httk: High-Throughput Toxicokinetics Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") using data obtained from... -
Federal
Case report: Survival after deliberate strychnine self-poisoning, with toxicokinetic data
U.S. Department of Health & Human Services —
Introduction Strychnine poisoning is uncommon, and in most severe cases, the patient dies before reaching hospital. The management of strychnine poisoning is well... -
Federal
Estimation of species- and sex-specific PFAS pharmacokinetics in mice, rats, and non-human primates using a Bayesian hierarchical methodology dataset
U.S. Environmental Protection Agency —
This dataset is a collection of .csv's for extracted data from the literature, processing code, and final analysis for manuscript. This dataset is not publicly... -
Federal
Exposure-response arrays for noncancer and cancer endpoints for p,p'-DDD and analogues
U.S. Environmental Protection Agency —
Data for the exposure-response arrays comparing effect levels for non-cancer and cancer endpoints for p,p'-DDD and analogues were sourced from the links provided.... -
Federal
Incorporating human exposure information in a weight of evidence approach to inform design of repeated dose animal studies
U.S. Environmental Protection Agency —
Dataset for "Incorporating human exposure information in a weight of evidence approach to inform design of repeated dose animal studies". This dataset is associated... -
Federal
Toxicokinetics of PFOS in rainbow trout
U.S. Environmental Protection Agency —
This ScienceHub entry was developed for the published paper: Consoer et al., 2016, Toxicokinetics of perfluorooctane sulfonate in rainow trout (Oncorhynchus mykiss),...
22 datasets found