4 datasets found
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Federal
MHC class I multimers
U.S. Department of Health & Human Services —
T lymphocytes play a key role in the immune response to both foreign and self peptide antigens, which they recognize in combination with MHC molecules. In the past it... -
Federal
A revival of the B cell paradigm for rheumatoid arthritis pathogenesis?
U.S. Department of Health & Human Services —
Dominant paradigms for the understanding of rheumatoid arthritis (RA) pathogenesis have changed over the years. A predominant role of B lymphocytes, and perhaps of... -
Federal
A geometric and algebraic view of MHC-peptide complexes and their binding properties
U.S. Department of Health & Human Services —
Background Major histocompatibility complex (MHC) molecules present peptides to T lymphocytes. It is of critical biological and medical importance to elucidate how... -
Federal
Cell-cell interactions in synovitis: Interactions between T lymphocytes and synovial cells
U.S. Department of Health & Human Services —
Mechanisms whereby T lymphocytes contribute to synovial inflammation in rheumatoid arthritis are poorly understood. Here we review data that indicate an important...
4 datasets found