14 datasets found
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Federal
Cytokine mRNA and protein expression in primary-culture and repeated-passage synovial fibroblasts from patients with rheumatoid arthritis
U.S. Department of Health & Human Services —
Constitutive mRNA expression and secretion of proinflammatory and anti-inflammatory cytokines was comparatively analyzed in rheumatoid arthritis (RA) synovial... -
Federal
p53 in rheumatoid arthritis: friend or foe?
U.S. Department of Health & Human Services —
The knowledge of transcription factors and proto-oncogenes has influenced the understanding of cell regulation, cell cycle, and apoptotic cell death in rheumatoid... -
Federal
The effects of 1α,25-dihydroxyvitamin D
U.S. Department of Health & Human Services —
The biologically active metabolite of vitamin D3, 1α,25-dihydroxyvitamin D3 [1α,25(OH)2D3], acts through vitamin D receptors, which were found in rheumatoid tissues... -
Federal
Molecular profile of synovial fibroblasts in rheumatoid arthritis depends on the stage of proliferation
U.S. Department of Health & Human Services —
The aim of this study was to explore the molecular profile of proliferating rheumatoid arthritis synovial fibroblasts (RA-SF). Total RNA was extracted from two... -
Federal
Fibroblast biology: Development and differentiation of synovial fibroblasts in arthritis
U.S. Department of Health & Human Services —
Synovial fibroblasts occur as two phenotypes - intimal and subintimal. The specialised intimal phenotype includes expression of uridine diphosphoglucose dehydrogenase... -
Federal
Research Article: Arthritis Research
U.S. Department of Health & Human Services —
Synovial fibroblasts (SFs) have become a major target for ex vivo gene transfer in rheumatoid arthritis (RA), but efficient transduction of RA-SFs still is a major... -
Federal
Mosaic chromosomal aberrations in synovial fibroblasts of patients with rheumatoid arthritis, osteoarthritis, and other inflammatory joint diseases
U.S. Department of Health & Human Services —
Chromosomal aberrations were comparatively assessed in nuclei extracted from synovial tissue, primary-culture (P-0) synovial cells, and early-passage synovial... -
Federal
Fibroblast biology: Synovial fibroblasts in rheumatoid arthritis - leading role or chorus line?
U.S. Department of Health & Human Services —
Fibroblast biology: Synovial fibroblasts in rheumatoid arthritis - leading role or chorus line? -
Federal
Fibroblast biology: Effector signals released by the synovial fibroblast in arthritis
U.S. Department of Health & Human Services —
There is mounting evidence indicating that the synovial fibroblast is a direct effector of tissue injury and matrix remodeling in inflammatory synovitis. Through the... -
Federal
Fibroblast biology: Signals targeting the synovial fibroblast in arthritis
U.S. Department of Health & Human Services —
Fibroblast-like cells in the synovial lining (type B lining cells), stroma and pannus tissue are targeted by many signals, such as the following: ligands binding to... -
Federal
Isolation and characterization of rheumatoid arthritis synovial fibroblasts from primary culture — primary culture cells markedly differ from fourth-passage cells
U.S. Department of Health & Human Services —
To reduce culture artifacts by conventional repeated passaging and long-term culture in vitro, the isolation of synovial fibroblasts (SFB) was attempted from... -
Federal
Fibroblast biology: Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis
U.S. Department of Health & Human Services —
There is growing evidence that activated synovial fibroblasts, as part of a complex cellular network, play an important role in the pathogenesis of rheumatoid... -
Federal
Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction
U.S. Department of Health & Human Services —
In the present study, we searched for mutant PTEN transcripts in aggressive rheumatoid arthritis synovial fibroblasts (RA-SF) and studied the expression of PTEN in... -
Federal
Kinesin-like protein CENP-E is upregulated in rheumatoid synovial fibroblasts
U.S. Department of Health & Human Services —
Our aim was to identify specifically expressed genes using RNA arbitrarily primed (RAP)-polymerase chain reaction (PCR) for differential display in patients with...
14 datasets found