8 datasets found
-
Federal
Mutational analysis of human profilin I reveals a second PI(4,5)-P
U.S. Department of Health & Human Services —
Background Profilin is a small cytoskeletal protein which interacts with actin, proline-rich proteins and phosphatidylinositol 4,5-bisphosphate (PI(4,5)-P2).... -
Federal
MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function
U.S. Department of Health & Human Services —
Background Three macromolecular assemblages, the lid complex of the proteasome, the COP9-Signalosome (CSN) and the eIF3 complex, all consist of multiple proteins... -
Federal
Partial identification by site-directed mutagenesis of a cell growth inhibitory site on the human galectin-1 molecule
U.S. Department of Health & Human Services —
Background Previous work, by us and others, has shown that mammalian galectins-1 have a growth-inhibitory activity for mammalian cells which is apparently independent... -
Federal
Identification of critical residues in loop E in the 5-HT
U.S. Department of Health & Human Services —
Background The serotonin type 3 receptor (5-HT3R) is a member of a superfamily of ligand gated ion channels. All members of this family share a large degree of... -
Federal
Color transitions in coral's fluorescent proteins by site-directed mutagenesis
U.S. Department of Health & Human Services —
Background Green Fluorescent Protein (GFP) cloned from jellyfish Aequorea victoria and its homologs from corals Anthozoa have a great practical significance as in... -
Federal
Probing substrate binding to Metallo-β-Lactamase L1 from
U.S. Department of Health & Human Services —
Background The metallo-β-lactamases are Zn(II)-containing enzymes that hydrolyze the β-lactam bond in penicillins, cephalosporins, and carbapenems and are involved in... -
Federal
Interconversion ofAnthozoaGFP-like fluorescent and non-fluorescent proteins by mutagenesis
U.S. Department of Health & Human Services —
Within the family of green fluorescent protein (GFP) homologs, one can mark two main groups, specifically, fluorescent proteins (FPs) and non-fluorescent or... -
Federal
Site-specific mutations of FtsZ - effects on GTPase and in vitro assembly
U.S. Department of Health & Human Services —
Background FtsZ, the major cytoskeletal protein in bacterial cytokinesis, assembles in vitro into protofilaments, which can further associate into sheets, bundles or...
8 datasets found