5 datasets found
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Federal
Doxycycline-induced expression of sense and inverted-repeat constructs modulates
U.S. Department of Health & Human Services —
Background A tetracycline-regulated (conditional) system for RNA interference (RNAi) would have many practical applications. Such a strategy was developed using RNAi... -
Federal
Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in
U.S. Department of Health & Human Services —
RNAi can be achieved by feeding worms Escherichia coli expressing dousble-stranded RNA corresponding to a specific gene. An optimized feeding method is presented that... -
Federal
Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses
U.S. Department of Health & Human Services —
Background Post-transcriptional gene silencing (PTGS) by short interfering RNA has opened up new directions in the phenotypic mutation of cellular genes. However, its... -
Federal
Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake
U.S. Department of Health & Human Services —
Background Several lines of evidence strongly suggest that agouti-related peptide (AGRP) plays a key role in the regulation of metabolic function but ablation of the... -
Federal
Quantitative polymerase chain reaction and confocal microscopy data describing cell penetrating peptide-mediated delivery of gene silencing agents to the invasive common reed Phragmites australis
Department of the Interior —
These data describe delivery of novel gene silencing agents (GSAs) to leaf tissue of the invasive common reed Phragmites australis ssp. australis using...
5 datasets found