81 datasets found
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Federal
Internet hand x-rays: A comparison of joint space narrowing and erosion scores (Sharp/Genant) of plain versus digitized x-rays in rheumatoid arthritis patients
U.S. Department of Health & Human Services —
Background The objective of the study is to examine the reliability of erosion and joint space narrowing scores derived from hand x-rays posted on the Internet... -
Federal
Correlation of the score for subjective pain with physical disability, clinical and radiographic scores in recent onset rheumatoid arthritis
U.S. Department of Health & Human Services —
Background To analyse the relationship between subjective pain score and other measures of clinical, radiographic and functional status; in particular Larsen... -
Federal
Is it Crohn's disease? A severe systemic granulomatous reaction to sulfasalazine in patient with rheumatoid arthritis
U.S. Department of Health & Human Services —
Background Sulfasalazine is a widely used anti-inflammatory agent in the treatment of inflammatory bowel disease and several rheumatological disorders. Although as... -
Federal
Cytokine mRNA and protein expression in primary-culture and repeated-passage synovial fibroblasts from patients with rheumatoid arthritis
U.S. Department of Health & Human Services —
Constitutive mRNA expression and secretion of proinflammatory and anti-inflammatory cytokines was comparatively analyzed in rheumatoid arthritis (RA) synovial... -
Federal
p53 in rheumatoid arthritis: friend or foe?
U.S. Department of Health & Human Services —
The knowledge of transcription factors and proto-oncogenes has influenced the understanding of cell regulation, cell cycle, and apoptotic cell death in rheumatoid... -
Federal
Insights into rheumatoid arthritis derived from the Sa immune system
U.S. Department of Health & Human Services —
The Sa system is a recently described immune system that has a specificity and positive predictive value of nearly 100% for rheumatoid arthritis (RA) in Asia, Europe... -
Federal
The effects of 1α,25-dihydroxyvitamin D
U.S. Department of Health & Human Services —
The biologically active metabolite of vitamin D3, 1α,25-dihydroxyvitamin D3 [1α,25(OH)2D3], acts through vitamin D receptors, which were found in rheumatoid tissues... -
Federal
Bone loss: Quantitative imaging techniques for assessing bone mass in rheumatoid arthritis
U.S. Department of Health & Human Services —
Osteoporosis is associated with low bone mass and microarchitectural deterioration of bone tissue with clinical manifestation of low trauma fractures. Rheumatoid... -
Federal
Genetics of rheumatoid arthritis: confronting complexity
U.S. Department of Health & Human Services —
The genetic basis for rheumatoid arthritis (RA) is likely to be extremely complex. Even the role of MHC genes remains to be fully defined, and may involve interactive... -
Federal
Macrophages in rheumatoid arthritis
U.S. Department of Health & Human Services —
The abundance and activation of macrophages in the inflamed synovial membrane/pannus significantly correlates with the severity of rheumatoid arthritis (RA). Although... -
Federal
Association of MHC and rheumatoid arthritis: HLA-DR4 and rheumatoid arthritis - studies in mice and men
U.S. Department of Health & Human Services —
Inherited susceptibility to rheumatoid arthritis (RA) is associated with the DRB1 genes encoding the human leukocyte antigen (HLA)-DR4 and HLA-DR1 molecules.... -
Federal
A new model for rheumatoid arthritis?
U.S. Department of Health & Human Services —
A chance observation has led to the development of a new murine model for inflammatory arthritis. Arthritis is induced, and transferred, by T-cell-dependent... -
Federal
Acute-phase serum amyloid A production by rheumatoid arthritis synovial tissue
U.S. Department of Health & Human Services —
Acute-phase serum amyloid A (A-SAA) is a major component of the acute-phase response. A sustained acute-phase response in rheumatoid arthritis (RA) is associated with... -
Federal
Molecular profile of synovial fibroblasts in rheumatoid arthritis depends on the stage of proliferation
U.S. Department of Health & Human Services —
The aim of this study was to explore the molecular profile of proliferating rheumatoid arthritis synovial fibroblasts (RA-SF). Total RNA was extracted from two... -
Federal
Association of MHC and rheumatoid arthritis: Why is rheumatoid arthritis associated with the MHC genetic region? An introduction
U.S. Department of Health & Human Services —
Association of MHC and rheumatoid arthritis: Why is rheumatoid arthritis associated with the MHC genetic region? An introduction -
Federal
Cardiovascular risk in rheumatoid arthritis versus osteoarthritis: acute phase response related decreased insulin sensitivity and high-density lipoprotein cholesterol as well as clustering of metabolic syndrome features in rheumatoid arthritis
U.S. Department of Health & Human Services —
Rheumatoid arthritis (RA) patients experience a markedly increased frequency of cardiovascular disease. We evaluated cardiovascular risk profiles in 79 RA patients... -
Federal
Cytokine-stimulated T cells induce macrophage IL-10 production dependent on phosphatidylinositol 3-kinase and p70S6K: implications for rheumatoid arthritis
U.S. Department of Health & Human Services —
IL-10 is an anti-inflammatory cytokine produced in the joint in rheumatoid arthritis by macrophages and infiltrating blood lymphocytes. Regulation of its expression... -
Federal
Association of MHC and rheumatoid arthritis: Regulatory role of HLA class II molecules in animal models of RA - studies on transgenic/knockout mice
U.S. Department of Health & Human Services —
Human leucocyte antigen (HLA) class II molecules have been shown to be associated with predisposition to rheumatoid arthritis (RA). We generated HLA-DR and DQ... -
Federal
Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset
U.S. Department of Health & Human Services —
An inception cohort of 238 patients having peripheral joint synovitis of less than 12 months duration was evaluated clinically and followed prospectively for 1 year... -
Federal
A revival of the B cell paradigm for rheumatoid arthritis pathogenesis?
U.S. Department of Health & Human Services —
Dominant paradigms for the understanding of rheumatoid arthritis (RA) pathogenesis have changed over the years. A predominant role of B lymphocytes, and perhaps of...
81 datasets found