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3 datasets found

Federal

Bone loss: Factors that regulate osteoclast differentiation - an update

U.S. Department of Health & Human Services —

Osteoclast activation is a critical cellular process for pathological bone resorption, such as erosions in rheumatoid arthritis (RA) or generalized bone loss. Among...
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Federal

Differentiation of monocytes into multinucleated giant bone-resorbing cells: two-step differentiation induced by nurse-like cells and cytokines

U.S. Department of Health & Human Services —

Bone resorption in the joints is the characteristic finding in patients with rheumatoid arthritis (RA). Osteoclast-like cells are present in the synovial tissues and...
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Federal

The role of TNF-receptor family members and other TRAF-dependent receptors in bone resorption

U.S. Department of Health & Human Services —

The contribution of osteoclasts to the process of bone loss in inflammatory arthritis has recently been demonstrated. Studies in osteoclast biology have led to the...
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3 datasets found

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