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Federal
Derivation and characterization of environmental hazard concentrations for chemical prioritization: a case study in the Great Lakes tributaries
U.S. Environmental Protection Agency —
Supplementary data for "Derivation and characterization of environmental hazard concentrations for chemical prioritization: a case study in the Great Lakes... -
Federal
CSS.3.2.2.1 NaKnowBase
U.S. Environmental Protection Agency —
Product CSS.3.2.2 includes three inter-related components, the delivery of which completes this product. This product represents updates to the NaKnowBase database,... -
Federal
Dataset for Chemical Signatures of neurodevelopmental disorders
U.S. Environmental Protection Agency —
This dataset contains the data, code and associated files for the manuscript Authored by Marable et al. This dataset is associated with the following publication:... -
Federal
Comparing the performance and coverage of selected in silico (liver) metabolism tools relative to reported studies in the literature to inform analogue selection in read-across: A case study
U.S. Environmental Protection Agency —
Dataset for journal article "Comparing the performance and coverage of selected in silico (liver) metabolism tools relative to reported studies in the literature to... -
Federal
KPF_Examining the Utility of In Vitro Bioactivity as a Protective Point of Departure: A Case Study_APCRA
U.S. Environmental Protection Agency —
The files and .R scripts here are provided to aid in understanding and reproduction of the analyses in the submitted paper, "Examining the Utility of In Vitro... -
Federal
Implementing in vitro bioactivity data to modernize priority setting of chemical inventories
U.S. Environmental Protection Agency —
All of the code used to analyze and report the data as well as build confidence in the approach is available as a supplementary RMarkdown report, and a tool to derive... -
Federal
Integrating Transcriptomic and Targeted New Approach Methodologies into a Tiered Framework for Chemical Bioactivity Screening
U.S. Environmental Protection Agency —
Dataset for Jesse Rogers et al., 'Integrating Transcriptomic and Targeted New Approach Methodologies into a Tiered Framework for Chemical Bioactivity Screening'... -
Federal
Comparison of in silico, in vitro, and in vivo toxicity benchmarks suggests a role for ToxCast data in ecological hazard assessment
U.S. Environmental Protection Agency —
Supplemental data for "Schaupp CM, Maloney EM, Mattingly K, Olker JH, Villeneuve DL. Comparison of in silico, in vitro, and in vivo toxicity benchmarks suggests a... -
Federal
Estimating Hepatotoxic Doses Using High-content Imaging in Primary Hepatocytes
U.S. Environmental Protection Agency —
This repository contains the necessary data, python source code and jupyter notebooks to reproduce the results from our manuscript, "Estimating Hepatotoxic Doses... -
Federal
EcoToxChip provides insights into pathway perturbation upon chlorantraniliprole exposure to larval fathead minnow
U.S. Environmental Protection Agency —
Supplemental materials for "EcoToxChip provides insights into pathway perturbation upon chlorantraniliprole exposure to larval fathead minnow". This dataset is... -
Federal
SSDn metal dataset
U.S. Environmental Protection Agency —
The dataset is an excel file that contains meta data, aquatic toxicity data, and summary tables. This dataset is associated with the following publication: Lambert,... -
Federal
ToxCast data and SeqAPASS results related to case study chemicals and targets referenced in Leveraging New Approach Methodologies to Complement Aquatic Life Criteria Derivation
U.S. Environmental Protection Agency —
Excel file containing ToxCast bioactivity data for carbaryl, celecoxib, chromium triacetate, HgCl2, nonylphenol, pentachlorophenol, PFOA, PFOS, pioglitazone, sodium... -
Federal
Combination of computational new approach methodologies for enhancing evidence of biological pathway conservation across species
U.S. Environmental Protection Agency —
Supplementary data for "Peter Schumann, Claudia Rivetti, Jade Houghton, Bruno Campos, Geoff Hodges, Carlie LaLone, Combination of computational new approach... -
Federal
Simulating toxicokinetic variability to identify susceptible and highly exposed populations
U.S. Environmental Protection Agency —
Data for "Breen, M., Wambaugh, J.F., Bernstein, A. et al. Simulating toxicokinetic variability to identify susceptible and highly exposed populations. J Expo Sci... -
Federal
Identifying Trans-Epithelial Effects of Inhaled Chemical Exposures on Stromal-Epithelial Oxidative Stress Dynamics in the Human Airway
U.S. Environmental Protection Agency —
Data include: trans-epithelial electrical resistance, FITC-dextran permeability, cell viability and gene expression (RNA and protein). This dataset is associated with... -
Federal
Screening for drinking water contaminants of concern using an automated exposure-focused workflow
U.S. Environmental Protection Agency —
Supplementary information and tables for "Isaacs, K.K., Wall, J.T., Paul Friedman, K. et al. Screening for drinking water contaminants of concern using an automated... -
Federal
The Residential Population Generator (RPGen): A tool to parameterize residential, demographic, and physiological data to model intraindividual exposure, dose, and risk
U.S. Environmental Protection Agency —
This repository contains scripts, input files, and some example output files for the Residential Population Generator, an R-based tool to generate synthetic human...