7 datasets found
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Federal
Analysis of stress- and host cell-induced expression of the
U.S. Department of Health & Human Services —
Background The gene encoding the inorganic pyrophosphatase (PPase) of the intracellular pathogen Legionella pneumophila is induced during intracellular infection, but... -
Federal
Identification of two
U.S. Department of Health & Human Services —
Background The ability of Mycobacterium tuberculosis to survive and replicate in macrophages is crucial for the mycobacterium's ability to infect the host and cause... -
Federal
Research Article: BMC Infectious Diseases
U.S. Department of Health & Human Services —
Background Pyrazinamide (PZA) is among the first-line drugs for the treatment of tuberculosis. In vitro, it kills semidormant mycobacteria only at low pH. The purpose... -
Federal
The ESAT-6 gene cluster of
U.S. Department of Health & Human Services —
Background The genome of Mycobacterium tuberculosis H37Rv has five copies of a cluster of genes known as the ESAT-6 loci. These clusters contain members of the CFP-10... -
Federal
Serial counts of
U.S. Department of Health & Human Services —
Background Since the sterilising activity of new antituberculosis drugs is difficult to assess by conventional phase III studies, surrogate methods related to... -
Federal
Frequency of tuberculous and non-tuberculous mycobacteria in HIV infected patients from Bogota, Colombia
U.S. Department of Health & Human Services —
Background The prevalence of infections by Mycobacterium tuberculosis and non-tuberculous Mycobacterium species in the HIV-infected patient population in Colombia was... -
Federal
Mycosin-1, a subtilisin-like serine protease of
U.S. Department of Health & Human Services —
Background Exported proteases are commonly associated with virulence in bacterial pathogens, yet there is a paucity of information regarding their role in...
7 datasets found