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3 datasets found

Federal

IFN-gamma transgenic mice: clues to the pathogenesis of systemic lupus erythematosus?

U.S. Department of Health & Human Services —

Transgenic mice overexpressing IFN-γ in the epidermis develop an inflammatory skin disease resembling cutaneous lupus erythematosus shortly after birth. By 3 months...
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Federal

The role of IFN-gamma in systemic lupus erythematosus: a challenge to the Th1/Th2 paradigm in autoimmunity

U.S. Department of Health & Human Services —

Cytokines play a critical role in regulating lymphoid cell responses to most antigenic stimuli, and it is therefore very likely that these molecules profoundly affect...
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Federal

IFN-γ production in response to

U.S. Department of Health & Human Services —

IFN-γ was measured in supernatants after in vitro stimulation of peripheral blood mononuclear cells with collagen type II (CII), purified protein derivative or...
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3 datasets found

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