8 datasets found
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Federal
Genetics of rheumatoid arthritis: confronting complexity
U.S. Department of Health & Human Services —
The genetic basis for rheumatoid arthritis (RA) is likely to be extremely complex. Even the role of MHC genes remains to be fully defined, and may involve interactive... -
Federal
Genetics of osteoarticular disorders, Florence, Italy, 22–23 February 2002
U.S. Department of Health & Human Services —
Osteoporosis (OP) and osteoarthritis (OA), the two most common age-related chronic disorders of articular joints and skeleton, represent a major public health problem... -
Federal
Genetic epidemiology: Giant cell arteritis and polymyalgia rheumatica
U.S. Department of Health & Human Services —
Giant cell arteritis (GCA) (temporal arteritis) and polymyalgia rheumatica (PMR) are common, frequently related conditions in people generally over 50 years of age.... -
Federal
Vitamin D receptor initiation codon polymorphism influences genetic susceptibility to type 1 diabetes mellitus in the Japanese population
U.S. Department of Health & Human Services —
Background Vitamin D has been shown to exert manifold immunomodulatory effects. Type 1 diabetes mellitus (T1DM) is regarded to be immune-mediated and vitamin D... -
Federal
Association of MHC and rheumatoid arthritis: HLA-DR4 and rheumatoid arthritis - studies in mice and men
U.S. Department of Health & Human Services —
Inherited susceptibility to rheumatoid arthritis (RA) is associated with the DRB1 genes encoding the human leukocyte antigen (HLA)-DR4 and HLA-DR1 molecules.... -
Federal
Genetic epidemiology: Psoriatic arthritis
U.S. Department of Health & Human Services —
The existence of psoriatic arthritis as a distinct clinical entity remains a topic of debate; some authors propose that it is simply the co-occurrence of psoriasis... -
Federal
Search for intracranial aneurysm susceptibility gene(s) using Finnish families
U.S. Department of Health & Human Services —
Background Cerebrovascular disease is the third leading cause of death in the United States, and about one-fourth of cerebrovascular deaths are attributed to ruptured... -
Federal
Cytochrome P450 2E1 polymorphism and nasopharyngeal carcinoma development in Thailand: a correlative study
U.S. Department of Health & Human Services —
Background Nasopharyngeal carcinoma (NPC) is a rare tumor in most parts of the world but occurs at relatively high frequency among people of Chinese descent. The...
8 datasets found