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3 datasets found

Federal

What have transgenic and knockout animals taught us about respiratory disease?

U.S. Department of Health & Human Services —

Over the past decade there has been a significant shift to the use of murine models for investigations into the molecular basis of respiratory diseases, including...
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Federal

Mutant loxP vectors for selectable marker recycle and conditional knock-outs

U.S. Department of Health & Human Services —

Background Gene disruption by targeted integration of transfected constructs becomes increasingly popular for studies of gene function. The chicken B cell line DT40...
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Federal

Gene targeting in mosquito cells: a demonstration of 'knockout' technology in extrachromosomal gene arrays

U.S. Department of Health & Human Services —

Background Gene targeting would offer a number of advantages over current transposon-based strategies for insect transformation. These include freedom from both...
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3 datasets found

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