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Federal
Datasets used in ORD-018902: Bisphenol A alternatives can effectively substitute for estradiol
U.S. Environmental Protection Agency —
Gene Expression Omnibus numbers only. This dataset is associated with the following publication: Mesnage, R., A. Phedonos, M. Arno, S. Balu, C. Corton, and M.... -
Federal
Data File 1: Metabolism of cyclic phenones in rainbow trout in vitro assays
U.S. Environmental Protection Agency —
Files contain summary reports of chemical and Mass Spectrometry raw and analyzed data used as basis for plot generation and text discussions in the Cyclic phenone... -
Federal
CERAPP: Collaborative Estrogen Receptor Activity Prediction Project
U.S. Environmental Protection Agency —
Data from a large-scale modeling project called CERAPP (Collaborative Estrogen Receptor Activity Prediction Project) demonstrating using predictive computational... -
Federal
Datasets in Gene Expression Omnibus used in the study ORD-020382: Evaluation of estrogen receptor alpha activation by glyphosate-based herbicide constituents
U.S. Environmental Protection Agency —
GEO accession number of the microarray study. This dataset is associated with the following publication: Mesnage, R., A. Phedonos, M. Biserni, M. Arno, S. Balu, C.... -
Federal
Phenone rtER binding Vtg_Tapper_A-jm6n_data set 20171002
U.S. Environmental Protection Agency —
Phenones and hydroxy benzophenones are widely used as UV radiation filters, and in the manufacturing of insecticides and pharmaceuticals. Understanding the ability of... -
Federal
Rainbow trout estrogen receptor (ER) competitive bindng and vitellogenin induction agonism/antagonism data for 94 chemicals
U.S. Environmental Protection Agency —
This dataset is from screening 94 diverse chemicals for estrogen receptor (ER) activation in a competitive rainbow trout ER binding assay and a trout liver slice... -
Federal
Organochlorine exposures influence on breast cancer risk and survival according to estrogen receptor status: a Danish cohort-nested case-control study
U.S. Department of Health & Human Services —
Background The relationship between breast cancer and organochlorine exposure is controversial and complex. As estrogen receptor positive and negative breast cancer... -
Federal
MulticyclicAromaticHydrocarbons rtER Vtg_Kolanczyk_A-bzkz_DataSet 20180828
U.S. Environmental Protection Agency —
A representative group of multicyclic aromatic hydrocarbons (MAHC) which can be further classified as bridged-ring (bridged-MAHC) or fused-ring (fused-MAHC) were... -
Federal
The Alginate Immobilization of Metabolic Enzymes (AIME) Platform Retrofits an Estrogen Receptor Transactivation Assay with Metabolic Competence
U.S. Environmental Protection Agency —
The objective of this study was to develop an approach to retrofit existing HTS assays with hepatic metabolism. The Alginate Immobilization of Metabolic Enzymes... -
Federal
Estrogen receptor alpha dinucleotide repeat polymorphism in Japanese patients with autoimmune thyroid diseases
U.S. Department of Health & Human Services —
Background The autoimmune thyroid diseases (AITDs), comprising Graves' disease (GD) and Hashimoto's thyroiditis (HT), appear to develop as a result of complex... -
Federal
Mass-spectrometric identification of cyclic phenone metabolites produced by rainbow trout liver slices
U.S. Environmental Protection Agency —
Dataset consists of 2 main files as follows: 1. All main and Supplemental MS final figures used for manuscript preparation for better viewing (pdf file). Figures are... -
Federal
PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling
U.S. Environmental Protection Agency —
Microarray datasets used in the analysis. This dataset is associated with the following publication: Rosen, M., K. Das, J. Rooney, B. Abbott, C. Lau, and C. Corton.... -
Federal
Increased endocrine activity of xenobiotic chemicals as mediated by metabolic activation - data set
U.S. Environmental Protection Agency —
Data set to support the manuscript "Increased endocrine activity of xenobiotic chemicals as mediated by metabolic activation". Contains analytical measurement of... -
Federal
Estrogenic Activity of Perfluoro Carboxylic and Sulfonic Acids in Rainbow Trout Estrogen Receptor Binding and Liver Slice Vtg mRNA Expression Assays
U.S. Environmental Protection Agency —
Data for "Estrogenic Activity of Perfluoro Carboxylic and Sulfonic Acids in Rainbow Trout Estrogen Receptor Binding and Liver Slice Vtg mRNA Expression Assays. Mark... -
Federal
Bisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen receptor-negative inflammatory breast cancer cells
U.S. Environmental Protection Agency —
Raw data and figures for Bisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen... -
Federal
Data submission for A-0k6f
U.S. Environmental Protection Agency —
List of biomarker genes used to predict estrogen receptor activity in MCF-7 cells; list of microarray accession numbers used in the study. This dataset is associated... -
Federal
Dataset for ORD-033374: A Gene Expression Biomarker Identifies Chemical Modulators of the Estrogen Receptor α (ERα) in a MCF-7 Microarray Compendium
U.S. Environmental Protection Agency —
Microarray experiments examined in the study. This dataset is associated with the following publication: Rooney, J., N. Ryan, J. Liu, R. Houtman, R. van Beuningen, J.... -
Federal
E1 E2 metabolism v1
U.S. Environmental Protection Agency —
Feminization of male fish and the role of endocrine-active chemicals in this phenomenon has been an area of intense study for many years. Estrone (E1), a natural... -
Federal
Chemical Screening in an Estrogen Receptor Transactivation Assay with Metabolic Competence
U.S. Environmental Protection Agency —
This is an original dataset generated at the U.S. EPA. Data was analyzed with the ToxCast Pipeline and deposited for release in invitroDB accessible via the U.S. EPA... -
Federal
ESR1 expression and DNA methylation data for FHM exposed to EE2
U.S. Environmental Protection Agency —
This dataset contains data for adult male fathead minnows exposed to EE2 (a synthetic estrogen). It is a targeted study on the response of the esr1 gene (expression...