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3 datasets found

Federal

Probing substrate binding to Metallo-β-Lactamase L1 from

U.S. Department of Health & Human Services —

Background The metallo-β-lactamases are Zn(II)-containing enzymes that hydrolyze the β-lactam bond in penicillins, cephalosporins, and carbapenems and are involved in...
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Federal

A role of proton transfer in peroxidase-catalyzed process elucidated by substrates docking calculations

U.S. Department of Health & Human Services —

Background Previous kinetic investigations of fungal-peroxidase catalyzed oxidation of N-aryl hydroxamic acids (AHAs) and N-aryl-N-hydroxy urethanes (AHUs) revealed...
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Federal

Kinetic comparison of tissue non-specific and placental human alkaline phosphatases expressed in baculovirus infected cells: application to screening for Down's syndrome

U.S. Department of Health & Human Services —

Background In humans, there are four alkaline phosphatases, and each form exibits a characteristic pattern of tissue distribution. The availability of an easy method...
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3 datasets found

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