79 datasets found
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Federal
Effects of metformin and its metabolite guanylurea on fathead minnow (Pimephales promelas) reproduction
U.S. Environmental Protection Agency —
Data associated with exposures of fathead minnows to varying concentrations of metformin and/or guanylurea. Includes three individual studies: ex vivo steroidogenesis... -
Federal
Screening the ToxCast Chemical Libraries for Binding to Transthyretin
U.S. Environmental Protection Agency —
Supporting information for "Screening the ToxCast Chemical Libraries for Binding to Transthyretin". This dataset is associated with the following publication:... -
Federal
In Vitro Screening for ToxCast Chemicals Binding to Thyroxine-Binding Globulin
U.S. Environmental Protection Agency —
Supporting Information for "In Vitro Screening for ToxCast Chemicals Binding to Thyroxine-Binding Globulin". This dataset is associated with the following... -
Federal
“The influence of control group reproduction on the statistical power of the Environmental Protection Agency’s Medaka Extended One Generation Reproduction Test (MEOGRT) data for simulations” Dataset
U.S. Environmental Protection Agency —
Excel spreadsheet that contains the raw fecundity data used to conduct power simulations specific to the MEOGRT reproductive assessment. This dataset is associated... -
Federal
Extracting and benchmarking emerging adverse outcome pathway knowledge
U.S. Environmental Protection Agency —
A collection of R scripts useful for extracting and analyzing adverse outcome pathway network data from the adverse outcome pathway wiki (aopwiki.org). This dataset... -
Federal
Datasets used in ORD-018902: Bisphenol A alternatives can effectively substitute for estradiol
U.S. Environmental Protection Agency —
Gene Expression Omnibus numbers only. This dataset is associated with the following publication: Mesnage, R., A. Phedonos, M. Arno, S. Balu, C. Corton, and M.... -
Federal
Datasets used in ORD-023417: Identification of Androgen Receptor Modulators in a Prostate Cancer Cell Line Microarray Compendium
U.S. Environmental Protection Agency —
Datasets used in ORD-023417: Identification of Androgen Receptor Modulators in a Prostate Cancer Cell Line Microarray Compendium. This dataset is associated with the... -
Federal
Dataset and code for cross species applicability of an AOP network for thyroid hormone system disruption
U.S. Environmental Protection Agency —
The data set consists of the following: 1) AOP-Wiki xml downloads from March 2022 used in constructing and evaluating the AOP network. 2) A literature database... -
Federal
Conversion of environmental estrone to estradiol by male fathead minnows
U.S. Environmental Protection Agency —
This data set describes experiments that were conducted to investigate whether exposure of male fathead minnows to environmentally-relevant estrone concentrations... -
Federal
Data File 1: Metabolism of cyclic phenones in rainbow trout in vitro assays
U.S. Environmental Protection Agency —
Files contain summary reports of chemical and Mass Spectrometry raw and analyzed data used as basis for plot generation and text discussions in the Cyclic phenone... -
Federal
A study of temporal effects of the model anti-androgen flutamide on components of the hypothalamic-pituitary-gonadal axis in adult fathead minnows
U.S. Environmental Protection Agency —
The aim of this study was to investigate temporal changes in the hypothalamic-pituitary-gonadal axis of fathead minnow treated with the model androgen receptor (AR)... -
Federal
Male Fathead Minnow Transcriptomes and Associated Chemical Analytes in Milwaukee Estuary System
U.S. Environmental Protection Agency —
This dataset presents the full hepatic transcriptomes of fathead minnows (Pimephales promelas) caged for four days at multiple sites within the Milwaukee Estuary area... -
Federal
Larval fathead minnow swim bladder inflation following exposure to 2-mercaptobenzothiazole
U.S. Environmental Protection Agency —
In this study, a hypothesized adverse outcome pathway (AOP) linking inhibition of thyroid peroxidase (TPO) activity to impaired swim bladder inflation was... -
Federal
Identifying chemicals and mixtures of potential biological concern detected in passive samplers from Great Lakes tributaries using high-throughput data and biological pathways
U.S. Environmental Protection Agency —
Water-borne contaminants were monitored in 69 tributaries of the Laurentian Great Lakes in 2010 and 2014 using semipermeable membrane devices (SPMDs), and polar... -
Federal
Effects of the antimicrobial contaminant triclocarban, and co-exposure with the androgen 17beta-trenbolone, on reproductive function and ovarian transcriptome of the fathead minnow (Pimephales promelas).
U.S. Environmental Protection Agency —
Triclocarban (TCC) is a widely used antimicrobial agent that is routinely detected in surface waters. The present study was designed to examine TCC’s efficacy and... -
Federal
CERAPP: Collaborative Estrogen Receptor Activity Prediction Project
U.S. Environmental Protection Agency —
Data from a large-scale modeling project called CERAPP (Collaborative Estrogen Receptor Activity Prediction Project) demonstrating using predictive computational... -
Federal
Assessing utility of thyroid in vitro screening assays through comparisons to observed impacts in vivo
U.S. Environmental Protection Agency —
Supplementary data for "Stephanie A. Eytcheson, Jennifer H. Olker, Katie Paul Friedman, Michael W. Hornung, Sigmund J. Degitz, Assessing utility of thyroid in vitro... -
Federal
Secondary screening method for sodium-iodide symporter inhibition utilizing FRTL-5 cells data set
U.S. Environmental Protection Agency —
Data pertaining to a NIS-expressing cell line, FRTL-5 and it's screening capabilities for confirming inhibitors of NIS-mediated iodide uptake. This dataset is... -
Federal
The thyroid hormone system disrupting potential of resorcinol in fish
U.S. Environmental Protection Agency —
Supplemental materials for "The thyroid hormone system disrupting potential of resorcinol in fish". This dataset is associated with the following publication: Van... -
Federal
Iodotyrosine deiodinase: mRNA expression and experimental inhibition study in Xenopus laevis
U.S. Environmental Protection Agency —
This excel file contains the resultant data from a study on iodotyrosine deiodinase in the model amphibian species, Xenopus laevis. These data include: tadpole growth...
79 datasets found