91 datasets found
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Federal
Expression Data from International C.elegans Experiment 1st
National Aeronautics and Space Administration —
The effect of microgravity on gene expression in C.elegans was comprehensively analysed by DNA microarray. This is the first DNA microarray analysis for C.elegans... -
Federal
Effect of simulated microgravity on E. coli K12 MG1655 growth and gene expression
National Aeronautics and Space Administration —
This study demonstrates simulated microgravity effects on E. coli K 12 MG1655 when grown on LB medium supplemented with glycerol. The results imply that E. coli... -
Federal
Genechip analysis of bone marrow osteoprogenitors exposed to microgravity
National Aeronautics and Space Administration —
In March 2006 murine Bone Marrow Stromal Cells (BMSC) were flown in the Soyuz 12S to the International Space Station to investigate the effects of microgravity on... -
Federal
Genetic Dissection of the Spaceflight Transcriptome Responses in Plants: are some responses unnecessary?
National Aeronautics and Space Administration —
Experimentation on the International Space Station has reached the stage where repeated and nuanced transcriptome studies are beginning to illuminate the structural... -
Federal
Gene expression data from 4T1 irradiated tumors treated with TGFbeta blockade
National Aeronautics and Space Administration —
Accumulating data support the concept that ionizing radiation therapy (RT) has the potential to convert the tumor into an in situ individualized vaccine; however this... -
Federal
Temporal dynamics of the gut microbiota in people sharing a confined environment a 520-day ground-based space simulation MARS500
National Aeronautics and Space Administration —
The MARS500 project the longest ground-based space simulation ever provided us with a unique opportunity to trace the crew microbiota over 520 days of isolated... -
Federal
Transcriptomic analysis of skin from mice subjected to chronic low-dose radiation hindlimb unloading or a combination of both
National Aeronautics and Space Administration —
The purpose of this study was to evaluate transcriptional changes in mouse skin using a ground-based model for spaceflight. This model includes prolonged unloading... -
Federal
The development of Drosophila melanogaster during space flight
National Aeronautics and Space Administration —
In prospective human exploration of outer space the need to maintain a species over several generations under changed gravity conditions may arise. This paper reports... -
Federal
Low dose (0.04 Gy) irradiation (LDR) and hindlimb unloading (HLU) microgravity in mice: brain transcriptomic and epigenomic data
National Aeronautics and Space Administration —
The purpose of the present study was to evaluate damage in brain and eye in a ground-based model for spaceflight which includes prolonged unloading and low-dose... -
Federal
Expression data from SPHINX (SPaceflight of Huvec: an INtegrated eXperiment)
National Aeronautics and Space Administration —
Changes in the physical environment modulate cell responses and may lead to the impairment or even failure of tissue function as a result of mechanotransduction... -
Federal
The Arabidopsis spaceflight transcriptome: a comparison of whole plants to discrete root hypocotyl and shoot responses to the orbital environment
National Aeronautics and Space Administration —
Arabidopsis thaliana was evaluated for its response to the spaceflight environment in three replicated experiments on the International Space Station. Two approaches... -
Federal
Low dose ionizing radiation treated lymphoblastoid cells
National Aeronautics and Space Administration —
Irradiated cell lines exposed to 1-10 cGy 2 Lymphoblastoid cell lines (GM15510 and GM15036) irradiated 1 2.5 5 7.5 10 cGy RNA is isolated and labeled using a T7... -
Federal
Multi-omic investigations of mouse liver subjected to simulated spaceflight freezing and storage protocols
National Aeronautics and Space Administration —
This study compares standard laboratory protocols for tissue freezing and storage with a simulation of the delayed processing of liver specimens and long-term storage... -
Federal
T Cell Activation in Microgravity Compared to 1g (Earth s) Gravity
National Aeronautics and Space Administration —
This study tested the hypothesis that transcription of immediate early genes is inhibited in T cells activated in microgravity (uG). Immunosuppression during... -
Federal
Transcription profiling of rat response to changes in developmental stage - 3 types of tissue 3 gravity conditions 2 developmental conditions
National Aeronautics and Space Administration —
Transcriptional crosstalk between mammary gland liver and adipose tissue Experiment Overall Design: Pregnant and Lactating rats exposed to 3 gravity conditions -
Federal
Analysis of dust samples from the Russian part of the ISS
National Aeronautics and Space Administration —
Our study focuses on the hardiest microorganisms inhabiting the ISS in order to assess their diversity and capabilities to resist certain stresses. We specifically... -
Federal
Transcriptomic analysis of liver from mice subjected to simulated spaceflight euthanasia freezing and tissue preservation protocols
National Aeronautics and Space Administration —
To understand the molecular mechanisms affected by spaceflight it is essential to achieve high quality sample preservation on-orbit for downstream gene expression... -
Federal
Response of the EPI-200 human 3-D skin model to high and low doses of protons
National Aeronautics and Space Administration —
Accumulating data suggest that the biological responses to high and low doses of radiation are qualitatively different necessitating the direct study of low dose... -
Federal
Gene expression profiling in human fibroblast after low-LET irradiation
National Aeronautics and Space Administration —
Exposure to radiation provokes cellular responses controlled in part by gene expression networks. MicroRNAs (miRNAs) are small non-coding RNAs which mostly regulate... -
Federal
RNAseq analysis of the response of Arabidopsis thaliana to fractional gravity under blue-light stimulation during spaceflight
National Aeronautics and Space Administration —
Traveling to nearby extraterrestrial objects having a reduced gravity level (partial gravity) compared to Earth's gravity is becoming a realistic objective for space...
91 datasets found