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Federal
Obtaining reliable information from minute amounts of RNA using cDNA microarrays
U.S. Department of Health & Human Services —
Background High density cDNA microarray technology provides a powerful tool to survey the activity of thousands of genes in normal and diseased cells, which helps us... -
Federal
Sources of nonlinearity in cDNA microarray expression measurements
U.S. Department of Health & Human Services —
Background A key assumption in the analysis of microarray data is that the quantified signal intensities are linearly related to the expression levels of the... -
Federal
Within the fold: assessing differential expression measures and reproducibility in microarray assays
U.S. Department of Health & Human Services —
Fold-change' cutoffs have been widely used in microarray assays to identify genes that are differentially expressed. More accurate measures are required to identify...