8 datasets found
-
Federal
Fragmentation of Golgi complex and Golgi autoantigens during apoptosis and necrosis
U.S. Department of Health & Human Services —
Anti-Golgi complex autoantibodies are found primarily in patients with Sjögren's syndrome and systemic lupus erythematosus, although they are not restricted to these... -
Federal
IFN-gamma transgenic mice: clues to the pathogenesis of systemic lupus erythematosus?
U.S. Department of Health & Human Services —
Transgenic mice overexpressing IFN-γ in the epidermis develop an inflammatory skin disease resembling cutaneous lupus erythematosus shortly after birth. By 3 months... -
Federal
What you should know about PR3-ANCA: Structural aspects of antibodies to proteinase 3 (PR3)
U.S. Department of Health & Human Services —
Reactive antigenic epitopes on presumed autoantigens of biologic interest have been examined by many researchers. The central third complementarity-determining region... -
Federal
B cells in rheumatoid arthritis
U.S. Department of Health & Human Services —
Normally the immune response is restricted to the peripheral secondary lymphoid organs. However, additional ectopic lymphoid tissue may develop at chronic sites of... -
Federal
Autoimmune response to U1 small nuclear ribonucleoprotein (U1 snRNP) associated with cytomegalovirus infection
U.S. Department of Health & Human Services —
The induction of autoantibodies to U1 small nuclear ribonucleoprotein (U1 snRNP) complexes is not well understood. We present evidence that healthy individuals with... -
Federal
Low prevalence of liver-kidney microsomal autoantibodies of type 1 (LKM
U.S. Department of Health & Human Services —
Background Hepatitis C is a serious problem on the Greek island of Crete, where a high prevalence of antibodies against hepatitis C (anti-HCV) has recently been... -
Federal
Autoantibody systems in rheumatoid arthritis: specificity, sensitivity and diagnostic value
U.S. Department of Health & Human Services —
The diagnosis of rheumatoid arthritis (RA) is primarily based on clinical symptoms, so it is often difficult to diagnose RA in very early stages of the disease. A... -
Federal
Citrullination: a small change for a protein with great consequences for rheumatoid arthritis
U.S. Department of Health & Human Services —
A new autoantibody activity, which is almost 100% specific for rheumatoid arthritis (RA), has been found. The essential part of the B-cell epitope is a modified form...
8 datasets found