35 datasets found
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Federal
MetaData_2025-01-27_Inhibition-of-Fin-Regeneration-in-Fathead-Minnow-(Pimephales-promelas)-by-a-Potent-Synthetic-Glucocorticoid-and-Development-of-Adverse-Outcome-Pathway-334
U.S. Environmental Protection Agency —
Metadata for both preliminary and definitive studies, including water quality parameters, experimental takedown data, fin measurements, and RT-PCR data. This dataset... -
Federal
Gupta 2025 Dipentyl phthalate testis dose response dataset
U.S. Environmental Protection Agency —
Dataset includes summary data for all endpoints measured in the experiments reported in the manuscript. This dataset is associated with the following publication:... -
Federal
Data from ex vivo Kainic acid proteomic studies: Hippocampus and Cortex proteomic results
U.S. Environmental Protection Agency —
Dataset includes whole proteome results following acute kainic acid exposure in adult Long Evans rats. Samples are ex vivo brain tissues, specifically the... -
Federal
Dataset and code for cross species applicability of an AOP network for thyroid hormone system disruption
U.S. Environmental Protection Agency —
The data set consists of the following: 1) AOP-Wiki xml downloads from March 2022 used in constructing and evaluating the AOP network. 2) A literature database... -
Federal
Developmental toxicity of PFO4DA and PFO5DoA assessed using hepatic transcriptomics and serum metabolomics
U.S. Environmental Protection Agency —
Production of per- and polyfluoroalkyl substances (PFAS) has shifted from long-chain perfluoroalkyl acids to short-chain compounds and those with ether bonds in the... -
Federal
Ammonium Perchlorate - Serum dosimetry, neurotoxicity and resilience of the neonatal rat thyroid system
U.S. Environmental Protection Agency —
Perchlorate is an environmental contaminant that interferes with iodine uptake via the NIS transporter into the thyroid gland, reducing thyroid hormone (TH)... -
Federal
Dataset for Publication PFAS Modulate Osmotic Signaling Independent of Gravimetric Changes in the Rat Uterus
U.S. Environmental Protection Agency —
Uterotrophic assay data analysis from gene arrays and uterine weights. This dataset is associated with the following publication: Dixon, A., E. Rowan, A. Yackley, and... -
Federal
Triethyl Tin Data: Nerve Excitability, Body Weight, Functional Observational Battery, Histology, and raw Lipidomics data after single exposure to 0, 3, 4.4 or 6.5 mg/kg triethyl tin.
U.S. Environmental Protection Agency —
Nerve Excitability, Body Weight, Functional Observational Battery, Histology, and raw Lipidomics data after single exposure to 0, 3, 4.4 or 6.5 mg/kg triethyl tin. -
Federal
Structural Malformations in Brain Accompany Developmental Perchlorate Exposure in Rodents
U.S. Environmental Protection Agency —
Structural defects in the rat brain associated with maternal exposure to ammonium perchlorate accompanied reductions in circulating levels of thyroid hormone in the... -
Federal
Cumulative maternal and neonatal effects of combined exposure to a mixture of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) during pregnancy in the Sprague-Dawley rat data set
U.S. Environmental Protection Agency —
Data set contains summary data (mean, standard error, sample size) for all measured endpoints from all experiments reported in the published manuscript. This dataset... -
Federal
Caged and resident fish, Newton Creek, Superior WI, 2017
U.S. Environmental Protection Agency —
In 2017 the Wisconsin DNR reported observation of a high incidence of fish with fin erosion in Newton Creek, which originates near the site of the Calumet (later... -
Federal
The thyroid hormone system disrupting potential of resorcinol in fish
U.S. Environmental Protection Agency —
Supplemental materials for "The thyroid hormone system disrupting potential of resorcinol in fish". This dataset is associated with the following publication: Van... -
Federal
Transcriptomic data (GSE199233) and CEBs data (from Blake et al. 2020) for maternal and fetal endpoints following gestational exposure to PFOA or GenX
U.S. Environmental Protection Agency —
Maternal and fetal liver gene expression and pathway changes following exposure to perfluorooctanoic acid (PFOA) or hexafluoropropylene oxide-dimer acid (HFPO-DA)... -
Federal
Evans_2022_PFAS_in-vitro_manuscript_ScienceHub_2022-6-24
U.S. Environmental Protection Agency —
Dataset of medium throughput (96 well plate) in vitro nuclear receptor activation assays for peroxisome proliferator activated receptor alpha (PPARa), PPAR gamma... -
Federal
MS Datasets and Analyses for Shenandoah River FHM Metabolomics
U.S. Environmental Protection Agency —
MS Datasets and Analyses for Shenandoah River FHM Metabolomics -
Federal
Conley 2025 Maternal and neonatal effects of PFHxS dataset
U.S. Environmental Protection Agency —
Dataset includes summary statistics (mean, standard error, sample size) for all endpoints measured and reported from the the experiments described in the published... -
Federal
Methods for Thyroid Hormone Measurements in Neonatal Rat Brain
U.S. Environmental Protection Agency —
Serum and brain thyroid hormone measurements in rat brain. This dataset is associated with the following publication: Gilbert, M., J. Ford, C. Riutta, K.... -
Federal
Thyroid Hormone Insufficiency Alters the Pattern of Expression of the Ca2+-Binding Proteins in the Rat Neonatal Cortex
U.S. Environmental Protection Agency —
Dataset includes various results from two studies: the first study being a pilot study (M1123) and the second including dose response (M1224). In both studies,... -
Federal
WM_betasdam Final data and code
U.S. Environmental Protection Agency —
Hydrological, biological, geomorphological, and geospatial datasets collected from the Western Mountains of the United States used to develop the beta SDAM for the...
35 datasets found