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Federal
Isolation and characterization of rheumatoid arthritis synovial fibroblasts from primary culture — primary culture cells markedly differ from fourth-passage cells
U.S. Department of Health & Human Services —
To reduce culture artifacts by conventional repeated passaging and long-term culture in vitro, the isolation of synovial fibroblasts (SFB) was attempted from... -
Federal
Assessing the knowledge of bronchial asthma among primary health care physicians in Crete: A pre- and post-test following an educational course
U.S. Department of Health & Human Services —
Aim To assess the level of knowledge for bronchial asthma of the primary healthcare physicians serving a rural population on the island of Crete, both before and... -
Federal
Development and use of a computer program to detect potentially inappropriate prescribing in older adults residing in Canadian long-term care facilities
U.S. Department of Health & Human Services —
Background Inappropriate prescribing has been estimated to be as high as 40% in long-term care. The purpose of this study was to develop a computer program that... -
Federal
Apoptosis and signalling in acid sphingomyelinase deficient cells
U.S. Department of Health & Human Services —
Background Recent evidence suggests that the activation of a non-specific lipid scramblase during apoptosis induces the flipping of sphingomyelin from the cell... -
Federal
Assessment of performance of four mortality prediction systems in a Saudi Arabian intensive care unit
U.S. Department of Health & Human Services —
Introduction The purpose of this study is to assess the performance of Acute Physiology and Chronic Health Evaluation (APACHE) II, Simplified Acute Physiology Score... -
Federal
A conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signaling pathways via PLC Gamma 2 in B cells
U.S. Department of Health & Human Services —
Background Bruton's tyrosine kinase (Btk) is essential for B cell development and function. Mutations of Btk elicit X-linked agammaglobulinemia in humans and X-linked... -
Federal
Four signature motifs define the first class of structurally related large coiled-coil proteins in plants.
U.S. Department of Health & Human Services —
Background Animal and yeast proteins containing long coiled-coil domains are involved in attaching other proteins to the large, solid-state components of the cell.... -
Federal
Clinical review: Hypertonic saline resuscitation in sepsis
U.S. Department of Health & Human Services —
The present review discusses the hemodynamic effects of hypertonic saline in experimental shock and in patients with sepsis. We comment on the mechanisms of action of... -
Federal
'CFTR-opathies': disease phenotypes associated with cystic fibrosis transmembrane regulator gene mutations
U.S. Department of Health & Human Services —
Cystic fibrosis is a genetic disease that is associated with abnormal sweat electrolytes, sino-pulmonary disease, exocrine pancreatic insufficiency, and male... -
Federal
Accuracy of prognosis estimates by four palliative care teams: a prospective cohort study
U.S. Department of Health & Human Services —
Background Prognosis estimates are used to access services, but are often inaccurate. This study aimed to determine the accuracy of giving a prognosis range. Methods... -
Federal
A tandem repeats database for bacterial genomes: application to the genotyping of
U.S. Department of Health & Human Services —
Background Some pathogenic bacteria are genetically very homogeneous, making strain discrimination difficult. In the last few years, tandem repeats have been... -
Federal
Beat-to-beat changes in stroke volume precede the general circulatory effects of mechanical ventilation: a case report
U.S. Department of Health & Human Services —
Background: The haemodynamic as well as the ventilatory consequences of mechanical ventilation can be harmful in critically ill neonates. Newly developed ventilatory... -
Federal
Human members of the eukaryotic protein kinase family
U.S. Department of Health & Human Services —
Publicly available genetic sequence data were searched for human sequences that potentially represent protein kinases, important players in virtually every signaling... -
Federal
Are women and providers satisfied with antenatal care? Views on a standard and a simplified, evidence-based model of care in four developing countries
U.S. Department of Health & Human Services —
Background This study assessed women and providers' satisfaction with a new evidence-based antenatal care (ANC) model within the WHO randomized trial conducted in... -
Federal
Respirable antisense oligonucleotides: a new drug class for respiratory disease
U.S. Department of Health & Human Services —
Respirable antisense oligonucleotides (RASONs), which attenuate specific disease-associated mRNAs, represent a new class of respiratory therapeutics with considerable... -
Federal
Training practitioners in preparing systematic reviews: a cross-sectional survey of participants in the Australasian Cochrane Centre training program
U.S. Department of Health & Human Services —
Background Although systematic reviews of health care interventions are an invaluable tool for health care providers and researchers, many potential authors never... -
Federal
Clinical features of culture-proven
U.S. Department of Health & Human Services —
Objective This retrospective chart review describes the epidemiology and clinical features of 40 patients with culture-proven Mycoplasma pneumoniae infections at King... -
Federal
Bridging case-control studies and randomized trials
U.S. Department of Health & Human Services —
Randomized trials and observational studies, such as case-control studies, are often seen as opposing approaches. However, in many instances results obtained by... -
Federal
Hepatitis C virus whole genome position weight matrix and robust primer design
U.S. Department of Health & Human Services —
Background The high degree of sequence heterogeneity found in Hepatitis C virus (HCV) isolates, makes robust nucleic acid-based assays difficult to generate.... -
Federal
A Problem with the Individual Approach in the WHO Health Inequality Measurement
U.S. Department of Health & Human Services —
Background In the World Health Report 2000, the World Health Organization made the controversial choice to measure inequality across individuals rather than across...