169 datasets found
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Federal
MicroRNA expression of C. elegans in space environment
National Aeronautics and Space Administration —
Entire microRNA expression were analyzed using the Filgen Array miRNA Caenorhabditis elegans 232 probes (Filgen). In the microRNA expression analysis we compared the... -
Federal
Rodent Research-3-CASIS: Mouse kidney transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse quadriceps muscle transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
Genechip analysis of bone marrow osteoprogenitors exposed to microgravity
National Aeronautics and Space Administration —
In March 2006 murine Bone Marrow Stromal Cells (BMSC) were flown in the Soyuz 12S to the International Space Station to investigate the effects of microgravity on... -
Federal
Effect of acute muscle unloading on soleus and gastrocnemius muscle gene expression
National Aeronautics and Space Administration —
Gene expression changes induced by acute skeletal muscle unloading which leads to physiological changes including muscle atrophy fibre-type switching and loss of... -
Federal
BRIC-23 GeneLab Process Verification Test: Staphylococcus aureus transcriptomic proteomic and metabolomic data
National Aeronautics and Space Administration —
Microbes interact with humans in complex ways and understanding how they respond to the spaceflight environment is important to the success of future manned... -
Federal
Gene expression profiling in human fibroblast after low-LET irradiation
National Aeronautics and Space Administration —
Exposure to radiation provokes cellular responses controlled in part by gene expression networks. MicroRNAs (miRNAs) are small non-coding RNAs which mostly regulate... -
Federal
Gene expression profiling of PBL in response to ionising radiation and modeled microgravity
National Aeronautics and Space Administration —
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis... -
Federal
Gravitational signature of synchronized cell cultures in particular cell cycle stages
National Aeronautics and Space Administration —
Cell cycle and cell proliferation are decoupled under altered gravity conditions. We have previously shown that semisolid cell cultures of Arabidopsis suffer overall... -
Federal
Synergistic effects of space radiation and microgravity (miRNA WT and ced-1 mutant)
National Aeronautics and Space Administration —
Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still... -
Federal
mRNA expression profile in DLD-1 and MOLT-4 cancer cell lines cultured under Microgravity
National Aeronautics and Space Administration —
DLD-1 and MOLT-4 cell lines were cultured in a Rotating cell culture system to simulate microgravity and mRNA expression profile was observed in comparison to Static... -
Federal
Transcription profiling of Drosophila exposed to a levitation magnet for different lengths of time
National Aeronautics and Space Administration —
Drosophila samples were exposed to the levitation magnet inside a 25mm diameter tubes with 3 ml of yeast-based Drosophila food in the bottom and a chamber of only 5... -
Federal
Effect of simulated microgravity on E. coli K12 MG1655 growth and gene expression
National Aeronautics and Space Administration —
This study demonstrates simulated microgravity effects on E. coli K 12 MG1655 when grown on LB medium supplemented with glycerol. The results imply that E. coli... -
Federal
BASE-A space experiment with Rhodospirillum rubrum S1H
National Aeronautics and Space Administration —
R. rubrum S1H inoculated on solid minimal media was sent to the ISS in September 2006 (BASE-A experiment). After 10 days flight R. rubrum cultures returned back to... -
Federal
Gene expression profiling of C. elegans under various thermal conditions
National Aeronautics and Space Administration —
To realistically evaluate the effects of the environment in space it is necessary to understand the effects of external factors during sample transport from Earth to... -
Federal
DNA copy number analysis from mice with radiation-induced acute myeloid leukemia
National Aeronautics and Space Administration —
Certain mouse strains such as CBA C3H and RFM have high incidence of radiation-induced acute myeloid leukemia (AML). The data in this series wer generated by using... -
Federal
Microgravity effect on C. elegans N2/VC (CERISE 8days)
National Aeronautics and Space Administration —
Microgravity effect on C. elegans gene expression was analysed by whole genome microarray. The worms were cultivated under microgravity for 8 days in the Japanese... -
Federal
Gene-expression profiling of Saccharomyces cerevisiae irradiated by high-LET radiations
National Aeronautics and Space Administration —
Ionizing radiations are categorized by linear energy transfer (LET) into low-LET and high-LET. High-LET is considered to have a higher relative biological... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse gastrocnemius muscle transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
RAD51 Interconnects Between DNA Replication DNA Repair and Immunity
National Aeronautics and Space Administration —
RAD51 a multifunctional protein plays a central role in DNA replication and homologous recombination repair and is known to be involved in cancer development. We...
169 datasets found