2,009 datasets found
-
Federal
Multiple redundant sequence elements within the fission yeast
U.S. Department of Health & Human Services —
Background Some origins in eukaryotic chromosomes fire more frequently than others. In the fission yeast, Schizosaccharomyces pombe, the relative firing frequencies... -
Federal
The critically ill patient after hepatobiliary surgery
U.S. Department of Health & Human Services —
Background: We analyzed the causes and results of utilization of critical care services in the special care unit in patients after surgical procedures performed by... -
Federal
Overdistension in ventilated children
U.S. Department of Health & Human Services —
Ventilating patients with acute respiratory failure according to standardized recommendations can lead to varying volume–pressure (V-P) relationships and... -
Federal
How should an infected perinephric haematoma be drained in a tetraplegic patient with baclofen pump implanted in the abdominal wall? – A case report
U.S. Department of Health & Human Services —
Background We present a case to illustrate controversies in percutaneous drainage of infected, perinephric haematoma in a tetraplegic patient, who had implantation of... -
Federal
HaploinsufficientBmp4ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressure
U.S. Department of Health & Human Services —
Glaucoma is a blinding disease usually associated with high intraocular pressure (IOP). In some families, abnormal anterior segment development contributes to... -
Federal
Low agreement for assessing the risk of postoperative deep venous thrombosis when deciding prophylaxis strategies: a study using clinical vignettes
U.S. Department of Health & Human Services —
Background Several clinical practice guidelines (CPG) on antithrombotic prophylaxis in surgical patients help to decide about the prophylaxis strategy based on the... -
Federal
Sequence requirements for RNA strand transfer during nidovirus discontinuous subgenomic RNA synthesis
U.S. Department of Health & Human Services —
Nidovirus subgenomic mRNAs contain a leader sequence derived from the 5′ end of the genome fused to different sequences (‘bodies’) derived from the 3′ end. Their... -
Federal
Detection of fast light-activated H
U.S. Department of Health & Human Services —
Background Proteorhodopsin (pR) is a light-activated proton pump homologous to bacteriorhodopsin and recently discovered in oceanic γ-proteobacteria. One perplexing... -
Federal
Native interface of the SAM domain polymer of TEL
U.S. Department of Health & Human Services —
Background TEL is a transcriptional repressor containing a SAM domain that forms a helical polymer. In a number of hematologic malignancies, chromosomal... -
Federal
Anti-cytokine therapy in chronic destructive arthritis
U.S. Department of Health & Human Services —
Tumor necrosis factor (TNF) and interleukin-1 (IL-1) are considered to be master cytokines in chronic, destructive arthritis. Therapeutic approaches in rheumatoid... -
Federal
Binding specificity of
U.S. Department of Health & Human Services —
Background To better understand the molecular interactions of Bt toxins with non-target insects, we have examined the real-time binding specificity and affinity of... -
Federal
Glycogen synthase kinase3 beta phosphorylates serine 33 of p53 and activates p53's transcriptional activity
U.S. Department of Health & Human Services —
Background The p53 protein is activated by genotoxic stress, oncogene expression and during senescence, p53 transcriptionally activates genes involved in growth... -
Federal
Physiology in medicine: importance of hypoxic pulmonary vasoconstriction in maintaining arterial oxygenation during acute respiratory failure
U.S. Department of Health & Human Services —
Hypoxic pulmonary vasoconstriction continues to attract interest more than half a century after its original report because of persistent mystery about its... -
Federal
The cohesin complex: sequence homologies, interaction networks and shared motifs
U.S. Department of Health & Human Services —
Background: Cohesin is a macromolecular complex that links sister chromatids together at the metaphase plate during mitosis. The links are formed during DNA... -
Federal
An international survey of patients with thalassemia major and their views about sustaining life-long desferrioxamine use
U.S. Department of Health & Human Services —
Background Management of thalassemia major requires patients to have life-long access to a treatment regimen of regular blood transfusions coupled with iron chelation... -
Federal
On the species of origin: diagnosing the source of symbiotic transcripts
U.S. Department of Health & Human Services —
Background Most organisms have developed ways to recognize and interact with other species. Symbiotic interactions range from pathogenic to mutualistic. Some... -
Federal
Cellular senescence:ex vivop53-dependent asymmetric cell kinetics
U.S. Department of Health & Human Services —
Cellular senescence is a defining property of euploid cells in culture [1,2]. Cultures derived from cells explanted from tissues of a variety of animal species... -
Federal
Prediction of co-regulated genes in
U.S. Department of Health & Human Services —
Background Identification of co-regulated genes is essential for elucidating transcriptional regulatory networks and the function of uncharacterized genes. Although... -
Federal
Manipulation of gene expression by an ecdysone-inducible gene switch in tumor xenografts
U.S. Department of Health & Human Services —
Background Rapid, robust and reversible induction of transgene expression would significantly facilitate cancer gene therapy as well as allow the in vivo functional... -
Federal
Preferences of Mexican anesthesiologists for vecuronium, rocuronium, or other neuromuscular blocking agents: a survey
U.S. Department of Health & Human Services —
Background Several neuromuscular blocking (NMB) agents are available for clinical use in anesthesia. The present study was performed in order to identify preferences...
2,009 datasets found