79 datasets found
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Federal
Assessing reproductive effects of aromatase inhibition on fishes with group-synchronous oocyte development using western mosquitofish (Gambusia affinis) as a model
U.S. Environmental Protection Agency —
Predictive models and frameworks for linking inhibition of the enzyme aromatase, as measured in non-animal high throughput screening assays, to adverse effects on... -
Federal
Predicting Estrogenicity of a Group of Substituted Phenols_IATA
U.S. Environmental Protection Agency —
Data are summarized in a two-dimensional data matrix that was developed for each substance for hazard characterization (Tables S1–S3). In the horizontal direction of... -
Federal
Water Chemistry and Smallmouth Bass Biological Data From the Potomac River, Dargan, Maryland, 2013-2019
Department of the Interior —
Decades of poor reproductive success and young-of-the-year recruitment, in addition to adult mortality, has led to a decline in the smallmouth bass (SMB) population... -
Federal
Prior knowledge-based approach for associating contaminants with biological effects: a case study in the St. Croix river basin, MN, WI, USA.
U.S. Environmental Protection Agency —
Concentrations of 127 organic chemicals measured in water samples collected from five locations in proximity to two municipal wastewater treatment plants in the St.... -
Federal
Assessment of Endocrine Disruption in the Shenandoah River Watershed – Chemical and Biological Data from Mobile Laboratory Fish Exposures and Other Experiments Conducted during 2014, 2015, and 2016
Department of the Interior —
This data release presents chemical and biological results from investigations of water quality, fish endocrine disruption, and emergent insects in the Shenandoah... -
Federal
Year-round presence of neonicotinoid insecticides in tributaries to the Great Lakes, USA
U.S. Environmental Protection Agency —
To better understand the transport of neonicotinoid insecticides into the Great Lakes, monthly samples (October 2015-September 2016) were collected from 10... -
Federal
Evaluation of the potential effects of three chemicals on the hypothalamic-pituitary-thyroid (HPT) and hypothalamic-pituitary-gonadal (HPG) axes using the Larval Amphibian Growth and Development Assay (LAGDA)
U.S. Environmental Protection Agency —
Three chemicals, 2-ethylhexyl 4-hydroxybenzoate (2-EHHB), 5-chloro-2-(2,4-dichlorophenoxy) phenol (triclosan), and 4-nonylphenol, branched (4-NP) were evaluated using... -
Federal
Case study in 21st century ecotoxicology: Using in vitro aromatase inhibition data to predict reproductive outcomes in fish, in vivo.
U.S. Environmental Protection Agency —
Data set includes empirical results from 60 h, 10 d, and 21 d exposures of female fathead minnows to the fungicide imazalil as well as simulations from predictive... -
Federal
The effect of thyroperoxidase and deiodinase inhibition on anterior swim bladder inflation in the zebrafish
U.S. Environmental Protection Agency —
The data set provides all data that were reported in results, tables, and figures associated with Stinckens et al., "The effect of thyroperoxidase and deiodinase... -
Federal
Challenges and Opportunities for Translational Research on Congenital Anomalies of External Genitalia: Summary of an NIDDK/AUA Workshop
U.S. Environmental Protection Agency —
This was a summary article from a workshop and did not produce new data. This dataset is not publicly accessible because: This was a summary article from a workshop... -
Federal
Effects of early life stage exposure of largemouth bass to atrazine or a model estrogen (17α-ethinylestradiol)
Department of the Interior —
Largemouth base histological development and transcriptomic changes in gonad tissue after early life stage exposure to Atrazine... -
Federal
Case study in 21st century ecotoxicology: using in vitro aromatase inhibition data to predict short term in vivo responses in adult female fish
U.S. Environmental Protection Agency —
This research was designed to evaluate whether a biologically-based computational model aligned with an adverse outcome pathway (AOP) could effectively predict animal... -
Federal
A case study on the use of exposure-activity ratios (EARs) to prioritize sites, chemicals, and bioactivities of concern in Great Lakes waters
U.S. Environmental Protection Agency —
As a case study, chemical occurrence data from a 2012 study in the Great Lakes Basin along with the ToxCast™ effects database were used to calculate exposure-activity... -
Federal
Medaka Extended One-Generation Reproduction Test (MEOGRT) of 2-Ethylhexyl 4-Hydroxybenzoate
U.S. Environmental Protection Agency —
Evaluation of multigenerational effects of 2-ethylhexyl 4-hydroxybenzoate in Japanese medaka Abstract The Japanese medaka (Oryzias latipes) extended one-generation... -
Federal
Current use pesticides in larval amphibian tissues, amphibian pathogen and wetland sediment screening data from three northeastern National Wildlife Refuges, 2013-14
Department of the Interior —
The data include concentrations of current use pesticides in tissues of larval wood frog (Lithobates sylvaticus) and spotted salamander (Ambystoma maculatum) and the... -
Federal
Antiandrogenic effects of prochloraz in Xenopus laevis_data_Haselman et al_version_0_20171122
U.S. Environmental Protection Agency —
These data are represented in the tables and graphs in the journal article, Antiandrogenic effects following multiple life stage exposure to the fungicide prochloraz... -
Federal
Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways
U.S. Environmental Protection Agency —
A set of three proposed "hub" key events were used to link together a series of example adverse outcome pathway (AOP) descriptions that were previously not linked in... -
Federal
Effects of deiodinase inhibition on amphibian metamorphosis
U.S. Environmental Protection Agency —
This dataset contains in vitro and in vivo biochemical and apical (i.e., growth/development) data pertaining to iodotyrosine deiodinase inhibition in the African... -
Federal
Impaired swim bladder inflation in early-life stage fathead minnows exposed to a deiodinase inhibitor, iopanoic acid
U.S. Environmental Protection Agency —
The present study investigated whether inhibition of deiodinase, the enzyme which converts thyroxine (T4) to the more biologically-active form,...
79 datasets found