288 datasets found
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Federal
Microbiological and nutritional analysis of lettuce crops grown on the International Space Station-VEG01B
National Aeronautics and Space Administration —
Lettuce crops grown in the Veggie payload aboard ISS, harvested and returned for chemical, microbiological and molecular analysis -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse tibialis anterior muscle transcriptomic, proteomic, and epigenomic data
National Aeronautics and Space Administration —
NASA's Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
Transcription profiling of human MCF10A cells subjected to ionizing radiation and treatment with transforming growth factor beta-1
National Aeronautics and Space Administration —
Transforming growth factor beta-1 (TGFbeta) is a tumor suppressor during the initial stage of tumorigenesis, but it can switch to a tumor promoter during neoplastic... -
Federal
Delayed Cardiomyocyte Response to Total Body Particle Radiation Exposure - Identification of Regulatory Gene Network [proton]
National Aeronautics and Space Administration —
We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1... -
Federal
Bulk RNA sequencing and spatially resolved transcriptional profiling of hippocampi from mice flown on the RRRM-2 mission
National Aeronautics and Space Administration —
In the Rodent Research Reference Mission (RRRM-2), forty female C57BL/6NTac mice were flown on the International Space Station. To assess differences in outcomes due... -
Federal
ISS Bacillus Genomes
National Aeronautics and Space Administration —
SRA of spore forming Bacillus strains isolated from various areas of the ISS during Microbial tracking investigation -
Federal
Effects of Space Flight on Inflammasome Activation in the Brain of Mice (Hippocampus; ECLIA)
National Aeronautics and Space Administration —
Space exploration exposes astronauts to stressors that alter the immune response, rendering them vulnerable to infections and diseases. In this study, we aimed to... -
Federal
Impact of spaceflight on gene expression in cultured human mesenchymal stem/stromal cell
National Aeronautics and Space Administration —
With technological advancements, human's desire to explore space is growing and more people are staying longer at the international space station (ISS). The impact of... -
Federal
Spaceflight-Induced Gene Expression Profiles in the Mouse Brain Are Attenuated by Treatment with the Antioxidant BuOE - Cornu Ammonis 1
National Aeronautics and Space Administration —
The demands of deep space pose a health risk to the central nervous system that has long been a concern when sending humans to space. While little is known about how... -
Federal
Quantitative evaluation of bioaerosols in different particle size fractions collected on the International Space Station (ISS)
National Aeronautics and Space Administration —
Exposure to bioaerosols can negatively impact human health. On the International Space Station (ISS) this exposure differs to that on Earth due to lack of... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse quadriceps muscle transcriptomic, proteomic, and epigenomic data
National Aeronautics and Space Administration —
NASA's Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
HSFA2 functions in the physiological adaptation of undifferentiated plant cells to spaceflight microgravity environment
National Aeronautics and Space Administration —
The Heat Shock Factor A2 (HsfA2), as a part of the HSF network, is essential to the plant's response to almost any environmental stress and to the cellular... -
Federal
Effects of spaceflight on murine skeletal muscle gene expression
National Aeronautics and Space Administration —
Spaceflight results in a number of adaptations to skeletal muscle, including atrophy and shifts towards faster muscle fiber types. To identify changes in gene... -
Federal
Growth rate of mammary cancers arising in irradiated mice is associated with pattern of immune infiltrate
National Aeronautics and Space Administration —
To determine how host irradiation affects tumor profiles in 10 month aged mice treated with HZE or gamma irradiation. -
Federal
Single-molecule long-read methylation profiling reveals regional DNA methylation regulated by Elongator Complex Subunit 2 in Arabidopsis roots experiencing spaceflight
National Aeronautics and Space Administration —
The Advanced Plant Experiment-04 - Epigenetic Expression (APEX-04-EpEx) experiment onboard the International Space Station examined the spaceflight-altered cytosine... -
Federal
RR-1 and RR-3 mouse liver transcriptomics with and without ERCC control RNA spike-ins
National Aeronautics and Space Administration —
Proper interpretation of RNA sequencing data requires an understanding of assay sensitivity and sources of variability. To this end, the External RNA Control... -
Federal
Transcriptional profiling, protein expression profiling, and phosphoprotein profiling of kidneys from mice flown on the RR-10 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-10 Mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue... -
Federal
Transcriptional profiling of cerebellums from mice flown on the RR-23 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-23 missions (RR-23) was to better understand the effects of spaceflight on the eyes, specifically on the structure and function... -
Federal
Reproducible changes in gut microbiome reveal a shift in microbial and host metabolism during spaceflight
National Aeronautics and Space Administration —
Data were generated as part of a NASA-funded study (Turek F (PI) et al. Effects of Spaceflight on Gastrointestinal Microbiota in Mice: Mechanisms and Impact on Multi-... -
Federal
Root transcriptome remodeling of Arabidopsis in response to high levels of magnesium sulfate
National Aeronautics and Space Administration —
Martian regolith (unconsolidated surface material) is a potential medium for plant growth in bioregenerative life support systems during manned missions on Mars....
288 datasets found