-
Mechanical ventilation: lessons from the ARDSNet trial
The acute respiratory distress syndrome (ARDS) is an inflammatory disease of the lungs characterized clinically by bilateral pulmonary infiltrates, decreased pulmonary... -
Two C or not two C: recurrent disruption of Zn-ribbons, gene duplication, lineage-specific gene loss, and horizontal gene transfer in evolution of bacterial ribosomal proteins
Background Ribosomal proteins are encoded in all genomes of cellular life forms and are, generally, well conserved during evolution. In prokaryotes, the genes for most ribosomal... -
The effects of weather on fungal abundance and richness among 25 communities in the Intermountain West
Background Because moisture and temperature influence the growth of fungi, characterizing weather conditions favorable for fungi may be used to predict the abundance and... -
Open tension free repair of inguinal hernias; the Lichtenstein technique
Background Recurrences have been a significant problem following hernia repair. Prosthetic materials have been increasingly used in hernia repair to prevent recurrences. Their... -
Rational therapy of chronic venous insufficiency – chances and limits of the therapeutic use of horse-chestnut seeds extract
Background and methods We report two clinical studies, one already published, performed in patients with early and advanced chronic venous insufficiency (CVI). In both,... -
Prevalence of attention deficit/hyperactivity disorder among adults in obesity treatment
Background Bariatric patients showing poor "focus" during treatment more often failed to lose weight or maintain reduced weight. Evaluation of these patients identified a number... -
Cell adhesion and signaling on the fibronectin 1
Background The first type III repeat of fibronectin is known to be involved in fibronectin matrix assembly, and recombinant proteins from this type III repeat can inhibit cell... -
Do multiple outcome measures require p-value adjustment?
Background Readers may question the interpretation of findings in clinical trials when multiple outcome measures are used without adjustment of the p-value. This question arises... -
Human papillomavirus DNA in plasma of patients with cervical cancer
Background Human papillomavirus (HPV) is a crucial etiological factor for cervical cancer (CC) development. From a diagnostic view-point, the consistent presence of HPV in CC... -
Acetaminophen poisoning: an update for the intensivist
Acetaminophen overdose is common and can result from deliberate/nonstaggered or accidental/staggered ingestion. Patients presenting within 24 h of an acetaminophen overdose can... -
E-utilities (Entrez Programming Utilities)
E-utilities (Entrez Programming Utilities) are a set of eight server-side programs that provide a stable interface into the Entrez query and database system at the National... -
Third Party Annotation (TPA) Database
A database that contains sequences built from the existing primary sequence data in GenBank. The sequences and corresponding annotations are experimentally supported and have... -
Confounding factors in diagnosing brain death: a case report
Background Brain death is strictly defined medically and legally. This diagnosis depends on three cardinal neurological features: coma, absent brainstem reflexes, and apnea. The... -
Mutational analysis of human profilin I reveals a second PI(4,5)-P
Background Profilin is a small cytoskeletal protein which interacts with actin, proline-rich proteins and phosphatidylinositol 4,5-bisphosphate (PI(4,5)-P2). Crystallography,... -
Systematic reviews of complementary therapies – an annotated bibliography. Part 2: Herbal medicine
Background Complementary therapies are widespread but controversial. We aim to provide a comprehensive collection and a summary of systematic reviews of clinical trials in three... -
Sequence Read Archive (SRA)
The Sequence Read Archive (SRA) stores raw sequencing data from the next generation of sequencing platforms including Roche 454 GS System®, Illumina Genome Analyzer®, Applied... -
Platelet count and Interleukin 6 Gene polymorphism in healthy subjects
Background Interleukin 6 (IL-6) is thought to play important roles in the development of reactive thrombocytosis caused by inflammation by its stimulatory effect on... -
Clinical Table Search Service
Clinical Table Search Service (formerly "lforms-service") is a web service which software programs can use for querying clinical data tables. -
BioProject
The BioProject database links to data that have been or will be deposited into archival databases maintained at members of the International Nucleotide Sequence Database... -
Genetic epidemiology: Systemic lupus erythematosus
Systemic lupus erythematosus is the prototype multisystem autoimmune disease. A strong genetic component of susceptibility to the disease is well established. Studies of murine...
Official websites use .gov
A
.gov website belongs to an official government
organization in the United States.
Secure .gov websites use HTTPS
A
lock (
) or https:// means you’ve safely connected to
the .gov website. Share sensitive information only on official,
secure websites.