{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "John Wambaugh", "hasEmail": "mailto:wambaugh.john@epa.gov"}, "description": "The supplemental information for this paper includes chemical-specific analytical methods, raw instrument data for chemical concentration analysis, processed data for experiments on intrinsic hepatic clearance (CLint -- metabolism) and chemical fraction unbound in the presence of human plasma protein (fup). Figures showing the curve fits for determining CLint are provided. Finally, all data were released publicly as HTTK R Package v1.10.1. \n\nThis dataset is associated with the following publication:\nWambaugh, J., B. Wetmore, C. Ring, C. Nicolas, R. Pearce, G. Honda, R. Dinallo, D. Angus, J. Gilbert, T. Sierra, A. Badrinarayanan, B. Snodgrass, A. Brockman, C. Strock, R. Setzer, and R. Thomas. Assessing Toxicokinetic Uncertainty and Variability in Risk Prioritization.   TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA,  172(2): 235-251, (2019).", "distribution": [{"accessURL": "https://www.epa.gov/chemical-research/toxicity-forecaster-toxcasttm-data", "title": "https://www.epa.gov/chemical-research/toxicity-forecaster-toxcasttm-data"}, {"accessURL": "https://cran.r-project.org/package=httk", "title": "https://cran.r-project.org/package=httk"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1504435/SupTable4-ProcessedData.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "SupTable4-ProcessedData.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1504435/SupTable1-AnalyticalMethods.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "SupTable1-AnalyticalMethods.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1504435/SupTable2-RawPPBData.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "SupTable2-RawPPBData.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1504435/SupTable3-RawCLintData.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "SupTable3-RawCLintData.xlsx"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1504435/SupplementalFigures4.pdf", "mediaType": "application/pdf", "title": "SupplementalFigures4.pdf"}], "identifier": "https://doi.org/10.23719/1504435", "keyword": ["ExpoCast", "exposure"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2019-05-08", "programCode": ["020:095"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1093/toxsci/kfz205"], "rights": null, "title": "Assessing Toxicokinetic Uncertainty and Variability in Risk Prioritization"}