{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Katie Friedman", "hasEmail": "mailto:paul-friedman.katie@epa.gov"}, "description": "Dataset from Foster, M.J., et al., Evaluating structure-based activity in a high-throughput assay for steroid biosynthesis, Computational Toxicology, Vol 24, No. 100245, Nov 2022, DOI https://doi.org/10.1016/j.comtox.2022.100245\n\nThe work described herein was conducted in R software (version 4.0.2) and is available at GitHub (https://github.com/USEPA/CompTox-HTH295R-SAR) and the US EPA Clowder repository as well as in Supplemental File 1 as an html file including code and resultant output. \n\nThis dataset is associated with the following publication:\nFoster, M., G. Patlewicz, I. Shah, D. Haggard, R. Judson, and K. Friedman. Evaluating structure-based activity in a high-throughput assay for steroid biosynthesis.   Computational Toxicology. Elsevier B.V., Amsterdam,  NETHERLANDS, 24: 100245, (2022).", "distribution": [{"accessURL": "https://clowder.edap-cluster.com/datasets/62680e42e4b0e232136663ff", "title": "https://clowder.edap-cluster.com/datasets/62680e42e4b0e232136663ff"}, {"accessURL": "https://github.com/USEPA/CompTox-HTH295R-SAR", "title": "https://github.com/USEPA/CompTox-HTH295R-SAR"}], "identifier": "https://doi.org/10.23719/1529362", "keyword": ["steroidogenesis", "chemotypes", "structure-activity relationships", "Read-across", "in silico screening"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2022-06-23", "programCode": ["020:000"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1016/j.comtox.2022.100245", "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569244"], "rights": null, "title": "Evaluating structure-based activity in a high-throughput assay for steroid biosynthesis"}