{"@type": "dcat:Dataset", "accessLevel": "public", "bureauCode": ["026:00"], "contactPoint": {"@type": "vcard:Contact", "fn": "Open Science Data Repository Help Desk", "hasEmail": "mailto:arc-dl-osdr-help@mail.nasa.gov"}, "description": "Genomic and proteomic characterization of the Aspergillus niger isolate, JSC-093350089, collected from U.S. segment surfaces of the International Space Station (ISS) is reported, along with a comparison to the experimentally established strain ATCC 1015. Whole-genome sequencing of JSC-093350089 revealed enhanced genetic variance when compared to publicly available sequences of A. niger strains. Analysis of the isolate\u201a\u00c4\u00f4s proteome revealed significant differences in the molecular phenotype of JSC-093350089, including increased abundance of proteins involved in the A. niger starvation response, oxidative stress resistance, cell wall integrity and modulation, and nutrient acquisition. Together, these data reveal the existence of a distinct strain of A. niger onboard the ISS and provide insight into the molecular phenotype that is selected for by melanized fungal species inhabiting spacecraft environments.", "distribution": [{"@type": "dcat:Distribution", "downloadURL": "https://www.ebi.ac.uk/pride/archive/projects/PXD008588", "format": "BIN", "mediaType": "application/octet-stream"}, {"@type": "dcat:Distribution", "downloadURL": "https://osdr.nasa.gov/bio/repo/data/studies/OSD-260", "format": "BIN", "mediaType": "application/octet-stream"}], "identifier": "10.26030/7c74-jk03", "keyword": ["__"], "license": "https://www.usa.gov/government-works", "modified": "2026-04-06", "programCode": ["026:000"], "publisher": {"@type": "org:Organization", "name": "Open Science Data Repository"}, "theme": ["Biological and Physical Sciences"], "title": "Genomic and Proteomic characterization of Aspergillus niger isolated from the International Space Station"}