{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "David Mount", "hasEmail": "mailto:mount.dave@epa.gov"}, "describedBy": "https://pasteur.epa.gov/uploads/10.23719/1528369/documents/Saunders%20et%20al.%20ScienceHub%20entry_amended%20IVIVE%20model.xlsx", "describedByType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "description": "This paper described development of an in vitro/in vivo model that accounts for first pass clearance effects.  The model details are contained in the supporting information for the paper. \n\nThis dataset is associated with the following publication:\nSaunders, L., J. Nichols, J.A. Arnot, J. Armitage, and F. Wania. An amended in vitro\u2013in vivo extrapolation model that accounts for first pass clearance effects on chemical bioaccumulation in fish.   Environmental Science: Processes & Impacts. Royal Society of Chemistry, Cambridge,  UK, 25(4): 741-754, (2023).", "distribution": [{"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1528369/Saunders%20et%20al.%20ScienceHub%20entry_amended%20IVIVE%20model.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "Saunders et al. ScienceHub entry_amended IVIVE model.xlsx"}], "identifier": "https://doi.org/10.23719/1528369", "keyword": ["biotransformation", "in vitro-in vivo extrapolation", "Intestinal metabolism", "First-pass clearance", "bioaccumulation", "rainbow trout"], "license": "https://pasteur.epa.gov/license/sciencehub-license-non-epa-generated.html", "modified": "2023-02-09", "programCode": ["020:000"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1039/d2em00522k", "https://pasteur.epa.gov/uploads/10.23719/1528369/documents/Saunders%20et%20al.%20ScienceHub%20entry_amended%20IVIVE%20model.xlsx"], "rights": null, "title": "Saunders et al. Amended IVIVE model"}