{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Ann Richard", "hasEmail": "mailto:richard.ann@epa.gov"}, "description": "These new analysis builds on the baseline GenRA approach and presents a proof of concept of how other contexts of similarity namely physchem can be implemented into a search strategy for identification of analogues and how this impacts performance of read-across. Chemicals Involved: Same ToxRef dataset as used in the original GenRA manuscript. \n\nThis dataset is associated with the following publication:\nHelman, G., I. Shah, and G. Patlewicz. Extending the Generalised Read-Across approach (GenRA): A systematic analysis of the impact of physicochemical property information on read-across performance.   Computational Toxicology. Elsevier B.V., Amsterdam,  NETHERLANDS, 8: 34-50, (2018).", "distribution": [{"accessURL": "https://gaftp.epa.gov/COMPTOX/NCCT_Publication_Data/PatlewiczGrace/Extending_the_Generalised_Read-Across_approach_(GenRA)_A_systematic_analysis_of_the_impact_of_physicochemical_property_information_on_read-across_performance/", "title": "https://gaftp.epa.gov/COMPTOX/NCCT_Publication_Data/PatlewiczGrace/Extending_the_Generalised_Read-Across_approach_(GenRA)_A_systematic_analysis_of_the_impact_of_physicochemical_property_information_on_read-across_performance/"}], "identifier": "https://doi.org/10.23719/1503179", "keyword": ["Read-across", "generalised read-across", "GenRA", "physiochemical parameters", "ToxCast", "DSSTox"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2019-04-01", "programCode": ["020:095"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1016/j.comtox.2018.07.001"], "rights": null, "title": "Generalised Read-Across (GenRA) refinements"}