{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Mary Gilbert", "hasEmail": "mailto:gilbert.mary@epa.gov"}, "description": "behavioral measures of learning and memory in adult offspring of rats treated with thyroid hormone synthesis inhibitor, propylthiouracil.\nElectrophysiological measures of 'memory' in form of plasticity model known as long term potentiation (LTP)\nMolecular changes induced by LTP. \n\nThis dataset is associated with the following publication:\nGilbert , M., K. Sanchez-Huerta, and C. Wood. Mild Thyroid Hormone Insufficiency During Development Compromises Activity-Dependent Neuroplasticity in the Hippocampus of Adult Make Rats.   ENDOCRINOLOGY. Endocrine Society,    157(2): 774-87, (2016).", "distribution": [{"downloadURL": "https://pasteur.epa.gov/uploads/403/M0710_BDNF%20LTP%20Data.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "title": "M0710_BDNF LTP Data.xlsx"}], "identifier": "A-v42b-403", "keyword": ["fear conditioning", "spatial learning", "neuroplasticity", "brain development", "developmental hypothyroidism", "LTP", "BDNF", "neurotrophins", "activity-dependent plasticity", "hippocampus", "CSS", "children's health", "brain", "thyroid"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2015-10-27", "programCode": ["020:000"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1210/en.2015-1643"], "rights": null, "title": "Mild Thyroid Hormone Insufficiency During Development Compromises Activity-Dependent Neuroplasticity in the Hippocampus of Adult Male Rats"}