{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Thomas Knudsen", "hasEmail": "mailto:knudsen.thomas@epa.gov"}, "description": "The AOP concept was used to translate ToxCast high-throughput screening data into a ToxPi matrix of 1058 chemicals x 24 features ordered by predicted potential to disrupt angiogenesis. \n\nThis dataset is associated with the following publication:\nSaili, K., J. Franzosa, N. Baker, R. Ellis-Hutchings, R. Settivari, E. Carney, R. Spencer, T. Zurlinden, N. Kleinstreuer, S. Li, M. Xia, and T. Knudsen. Systems Modeling of Developmental Vascular Toxicity.   Current Opinion in Toxicology. Elsevier BV, AMSTERDAM,  NETHERLANDS, 15(1): 55-63, (2019).", "distribution": [{"accessURL": "https://gaftp.epa.gov/COMPTOX/NCCT_Publication_Data/Saili/jfranzos", "title": "https://gaftp.epa.gov/COMPTOX/NCCT_Publication_Data/Saili/jfranzos"}], "identifier": "https://doi.org/10.23719/1503433", "keyword": ["adverse outcome pathway", "angiogenesis", "5HPP-33", "TNP-470", "ToxCast", "Tox21", "vEmbryo", "virtual embryo", "virtual tissues", "tipping points"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2019-02-27", "programCode": ["020:095"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": ["https://doi.org/10.1016/j.cotox.2019.04.004"], "rights": null, "title": "Saili_AOP43_Systems Modeling of Developmental Vascular Toxicity"}