{"@type": "dcat:Dataset", "accessLevel": "public", "bureauCode": ["009:25"], "contactPoint": {"@type": "vcard:Contact", "fn": "NIH", "hasEmail": "mailto:info@nih.gov"}, "description": "The synovium lines the noncartilaginous surfaces of the diarthrodial\t\t  joints, and synovial tissue is also found in tendon sheaths and bursae [1]. Several rheumatic diseases are characterized by synovial\t\t  inflammation. In these conditions, descriptive studies of synovial biopsy\t\t  specimens may contribute to an understanding of the events that take placein vivo, and they complement experimental animal studies as well as\t\t  in-vitro studies. Examination of synovial tissue is generally more relevant\t\t  than synovial fluid analysis, except, for example, the analysis of neutrophils\t\t  and platelets, and studies of soluble mediators. Recently, there has been an\t\t  enormous upsurge in investigations of the pathological changes in the synovium\t\t  [2] because of the availability of new methods to obtain\t\t  synovial biopsy samples [3,4] and\t\t  because of the development of immunohistological methods, in-situ\t\t  hybridization, and the polymerase chain reaction. Moreover, the complementary\t\t  DNA microarray technology may hold great promise for synovial tissue analysis\t\t  in the future [5].", "distribution": [{"@type": "dcat:Distribution", "description": "Visit the original government dataset for complete information, documentation, and data access.", "downloadURL": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC128863/", "mediaType": "text/html", "title": "Official Government Data Source"}], "identifier": "https://healthdata.gov/api/views/gi2f-2zj3", "issued": "2025-07-14", "keyword": ["joint-inflammation", "nih", "rheumatology", "synovitis"], "landingPage": "https://healthdata.gov/d/gi2f-2zj3", "modified": "2025-09-29", "programCode": ["009:048"], "publisher": {"@type": "org:Organization", "name": "National Institutes of Health"}, "theme": ["NIH"], "title": "Current perspectives on synovitis"}