{"accessLevel": "public", "bureauCode": ["020:00"], "contactPoint": {"fn": "Laura Carlson", "hasEmail": "mailto:carlson.laura@epa.gov"}, "describedBy": "https://pasteur.epa.gov/uploads/10.23719/1532148/documents/PCB%20MiST%20Data%20Dictionary.docx", "describedByType": "application/vnd.openxmlformats-officedocument.wordprocessingml.document", "description": "The PCB Mixtures Similarity Tool (MiST) is an Excel-based tool that automates the process for determining whether two PCB mixtures are \"sufficiently similar\". Humans are exposed to complex mixtures of PCBs in the environment; however, only a small subset of PCB mixtures has been tested for toxicity. MiST was developed as a tool for risk assessors to evaluate how dose-response information for tested PCB mixtures may serve as a surrogate when assessing untested mixtures found in the environment.", "distribution": [{"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1532148/EPA_Talk%201_EPA%20Mixtures%20Practices_Rice_FINAL_508.pdf", "mediaType": "application/pdf", "title": "EPA_Talk 1_EPA Mixtures Practices_Rice_FINAL_508.pdf"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1532148/ICF_Talk%204_MiST%20Slides_3-16-22_Final_508.pdf", "mediaType": "application/pdf", "title": "ICF_Talk 4_MiST Slides_3-16-22_Final_508.pdf"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1532148/EPA_Talk3_Potency_Patlewicz_FINAL_508.pdf", "mediaType": "application/pdf", "title": "EPA_Talk3_Potency_Patlewicz_FINAL_508.pdf"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1532148/EPA%20_Talk%202_Mixtures%20Approaches_Gift%20and%20Carlson_FINAL_508.pdf", "mediaType": "application/pdf", "title": "EPA _Talk 2_Mixtures Approaches_Gift and Carlson_FINAL_508.pdf"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1532148/MiST%20User%20Guide_final.pdf", "mediaType": "application/pdf", "title": "MiST User Guide_final.pdf"}, {"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1532148/Mixtures%20Similarity%20Tool_Version%201.1_03_24_22.zip", "mediaType": "application/zip", "title": "Mixtures Similarity Tool_Version 1.1_03_24_22.zip"}], "identifier": "https://doi.org/10.23719/1532148", "keyword": ["Mixture Similarity", "Children's Environmental Health", "Benchmark Dose", "chemical mixtures", "PCB congeners", "PCBs"], "license": "https://pasteur.epa.gov/license/sciencehub-license.html", "modified": "2022-03-24", "programCode": ["020:000"], "publisher": {"name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": {"name": "U.S. Environmental Protection Agency", "subOrganizationOf": {"name": "U.S. Government"}}}, "references": null, "rights": null, "title": "Polychlorinated Biphenyls Mixtures Similarity Tool (MiST)"}