These data were developed to support an effort to understand how whooping cranes select stopover habitat in the presence of human infrastructure. Location and associated data came from whooping cranes (Grus americana) from the Aransas-Wood Buffalo Population, 2010–2016. We marked a sample of 57 whooping cranes with leg-mounted transmitters that acquired locations via the global positioning system (GPS) network and transmitted those data through the Argos satellite system. Cranes were captured either at their natal areas in and adjacent to Wood Buffalo National Park in Canada or at their southern terminus along the Texas Gulf Coast, USA. Data herein include 9,347 ground locations used by whooping cranes during migration coupled with 19 potentially available locations for each used location (see processing steps for more information). Predictor variables hypothesized to explain variation in space use were included for all locations (used and available).