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    • Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail

    Metadata Updated: January 22, 2026

    This study examined effects of the brominated flame retardant hexabromocyclododecane (HBCD) on the avian endocrine system. Japanese quail (Coturnix japonica) were exposed to multiple doses of HBCD over multiple generations through feed and by maternal deposition into the egg. Liver transcriptomes were examined to identify genes and pathways directly affected by HBCD to better understand the mechanisms of action in birds. RNA was extracted from liver of adults and embryos and analyzed (1x50 bp) on an Illumina HiSeq 2000. NCBI Biosample accessions and the raw counts that were input into the differential expression analysis are provided in this dataset. The raw sequence data are available at the NCBI Sequence Read Archive under Bioproject number PRJNA313931.

    Access & Use Information

    Public: This dataset is intended for public access and use. License: No license information was provided. If this work was prepared by an officer or employee of the United States government as part of that person's official duties it is considered a U.S. Government Work.

    Downloads & Resources

    Dates

    Metadata Created Date January 11, 2026
    Metadata Updated Date January 22, 2026

    Metadata Source

    Harvested from DOI USGS DCAT-US

    Other Data Resources

    Additional Metadata

    Resource Type Dataset
    Metadata Created Date January 11, 2026
    Metadata Updated Date January 22, 2026
    Publisher U.S. Geological Survey
    Maintainer
    Identifier http://datainventory.doi.gov/id/dataset/USGS_6658c353d34ef3137d35fa86
    Data Last Modified 2024-04-09T00:00:00Z
    Category geospatial
    Public Access Level public
    Bureau Code 010:12
    Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
    Metadata Catalog ID https://ddi.doi.gov/usgs-data.json
    Schema Version https://project-open-data.cio.gov/v1.1/schema
    Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
    Datagov Dedupe Retained 20260121204831
    Harvest Object Id 9bdab76c-3c4a-4802-8245-a1b95b765d95
    Harvest Source Id 2b80d118-ab3a-48ba-bd93-996bbacefac2
    Harvest Source Title DOI USGS DCAT-US
    Metadata Type geospatial
    Old Spatial {"type": "Polygon", "coordinates": -76.822929, 39.049052, -76.822929, 39.056917, -76.812630, 39.056917, -76.812630, 39.049052, -76.822929, 39.049052}
    Source Datajson Identifier True
    Source Hash b2454aa3e0e4543fe1879f25b6952a0fb8c09e7fa65a5ef768a95b7befdeef03
    Source Schema Version 1.1
    Spatial {"type": "Polygon", "coordinates": -76.822929, 39.049052, -76.822929, 39.056917, -76.812630, 39.056917, -76.812630, 39.049052, -76.822929, 39.049052}

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