These data were compiled to perform analyses of hydrologic change, changes in sediment transport, and channel change within Moenkopi Wash, Arizona. Objective(s) of our study were to quantify the magnitude and timing of changes in hydrology, sediment transport, and channel form within Moenkopi Wash and to determine the downstream effects of those changes on sediment delivery downstream to the Little Colorado River, and the Colorado River. These data represent instantaneous discharge records, suspended-sediment sample records, topographic survey data, historical aerial imagery, and channel polygons and centerlines mapped on the historical imagery. Instantaneous discharge records in this study began in 1926 and extend to 2022 and were collected at 5 different stream gages within Moenkopi Wash. Suspended-sediment samples were collected between 1948 and 2022 at four stream gage locations. Topographic datasets were collected by field surveys between 1940 and 2016 at five stream gage locations. Aerial imagery datasets were collected in the 1930s, 1952, 1968, 1979, 1992, 1997, 2007, 2013, and 2019. The 1968 and 1979 aerial imagery was collected by the U. S. Geological Survey. The 1952 imagery was collected by the U.S. Army Map Service. The 1992 and 1997 imagery were collected by the National Aerial Imagery Program. The 2007, 2013 and 2019 aerial images were collected by the National Agricultural Program. These data can be used to analyze changes in hydrology, sediment transport, and channel change within Moenkopi Wash.