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    • Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with Influenza A virus

    Metadata Updated: December 2, 2025

    An experimental challenge of Influenza A virus in genetically modified TMPRSS2 knockout pigs.

    Resources in this dataset:

    • Resource Title: Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with Influenza A virus File Name: TMPRSS2 dataset.xlsx Resource Description: Supporting data for: Nasal shedding of A/swine/Iowa/A02524480/2020 (IA/20) H1N1 by virus titration on cell culture or qRT-PCR; Infection of IA/20 H1N1 in WT and TMPRSS2-/- pigs; Immunohistochemical (IHC) staining of Influenza A virus nucleoprotein; Cytokine and chemokine panel performed on bronchioalveolar lavage fluid.

    Access & Use Information

    Public: This dataset is intended for public access and use. License: us-pd

    Downloads & Resources

    Dates

    Metadata Created Date March 30, 2024
    Metadata Updated Date December 2, 2025

    Metadata Source

    Harvested from USDA JSON

    Other Data Resources

    Additional Metadata

    Resource Type Dataset
    Metadata Created Date March 30, 2024
    Metadata Updated Date December 2, 2025
    Publisher Agricultural Research Service
    Maintainer
    Identifier 10.15482/USDA.ADC/1529793
    Data Last Modified 2025-11-21
    Public Access Level public
    Bureau Code 005:18
    Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
    Schema Version https://project-open-data.cio.gov/v1.1/schema
    Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
    Harvest Object Id 735d141e-5c16-4e09-9032-fe220500369a
    Harvest Source Id d3fafa34-0cb9-48f1-ab1d-5b5fdc783806
    Harvest Source Title USDA JSON
    License https://www.usa.gov/publicdomain/label/1.0/
    Old Spatial {"type": "Point", "coordinates": -93.617248535156, 42.044002396934}
    Program Code 005:040
    Source Datajson Identifier True
    Source Hash 0d4bf30b18fac3f1b4fef9632755421068d0b9d5529433273e49cd3d8ced42b8
    Source Schema Version 1.1
    Spatial {"type": "Point", "coordinates": -93.617248535156, 42.044002396934}
    Temporal 2022-10-01/2023-05-31

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