The MERRA-2 Stratospheric Composition Reanalysis of Aura MLS (M2-SCREAM) products produced at NASA’s Global Modeling and Assimilation Office (GMAO) are generated by assimilating MLS and OMI retrievals into the GEOS Constituent Data Assimilation System (CoDAS) driven by meteorological fields from MERRA-2. M2-SCREAM assimilates hydrochloric acid (HCl), nitric acid (HNO3), stratospheric water vapor (H2O), nitrous oxide (N2O) and ozone with a system equipped with a version of the GEOS general circulation model and a stratospheric chemistry model, StratChem. Assimilated fields are provided globally at 0.5° by 0.625° resolution at three-hourly frequencies from 2004/09/01 to 2024/09/30. Assimilation uncertainties for each of the assimilated constituents are calculated from the CoDAS statistical output (Wargan et al., 2022) and provided as global full-resolution three-dimensional monthly files. Data product updates in March 2024, as a result of Aura MLS “duty cycle” of 190-GHz measurements, include reduced availability of H2O, N2O and HNO3 retrievals resulting in expected M2-SCREAM data quality degradation. However, preliminary analysis shows that the GEOS CoDAS handles the reduced temporal data coverage well, indicating that the GEOS model accurately propagates information from past observations. Data product updates in June 2024 resulting from MLS version upgrade to v5.0 include discontinuities in assimilated H2O (throughout the stratosphere) and N2O (in the lower stratosphere). To note: MLS water vapor is about 0.5 ppmv lower in v5.0, and the vertical range of assimilated N2O data is 100 hPa, extended down from 68 hPa. GMAO is not aware of discontinuities in HCl, HNO3, and ozone related to the version switch.