Potential evapotranspiration (PET), and reference evapotranspiration (ETo) are estimated on an approximately 2-kilometer (approximately 0.019 degrees longitude and 0.018 degrees latitude) spatial grid and at a daily time-scale from January 1, 2020 to December 31, 2020 for the entire State of Florida. PET and ETo were computed on the basis of solar radiation, meteorological data (min/max temperature, min/max relative humidity, and mean wind speed at 2-meter height), and shortwave blue-sky albedo data for 2020. Solar radiation was computed from Geostationary Operational Environmental Satellite (GOES) sensor data; blue-sky albedo was computed from the Moderate Resolution Imaging Spectrometer (MODIS) MCD43A1 BRDF/Albedo data product; and meteorological data were obtained from weather stations maintained by the University of Florida—Florida Automated Weather Network (FAWN), the South Florida Water Management District (SFWMD), and the National Oceanic and Atmospheric Administration (NOAA). The average daily ETo and PET rates were 3.74 and 3.65 millimeters per day, respectively. Open source tools for managing the NetCDF files in this data release can be found at https://github.com/jbellino-usgs/Florida-GOES-ET.