2,009 datasets found
-
Federal
Association of MHC and rheumatoid arthritis: Association of RA with HLA-DR4 - the role of repertoire selection
U.S. Department of Health & Human Services —
Most patients with rheumatoid arthritis (RA) express HLA-DR4, HLA-DR1 or HLA-DR10. These alleles share a common amino acid motif in their third hypervariable regions:... -
Federal
To what degree does cognitive impairment in Alzheimer's disease predict dependence of patients on caregivers?
U.S. Department of Health & Human Services —
Background Patients with Alzheimer's disease experience a progressive loss of cognitive function, and the ability to independently perform activities of daily life.... -
Federal
The diagnostic value of liver biopsy
U.S. Department of Health & Human Services —
Background Since the introduction of molecular diagnostic tools such as markers for hepatitis C and different autoimmune diseases, liver biopsy is thought to be... -
Federal
Transcutaneous flow related variables measured in vivo: the effects of gender
U.S. Department of Health & Human Services —
Backgound The identification of potential sources of error is a crucial step for any new assessment technique. This is the case for transcutaneous variables, such as... -
Federal
Parallel evolution of histophagy in ciliates of the genus
U.S. Department of Health & Human Services —
Background Species of Tetrahymena were grouped into three complexes based on morphological and life history traits: the pyriformis complex of microstomatous forms;... -
Federal
Research that influences policy and practice – characteristics of operational research to improve malaria control in Mpumalanga Province, South Africa
U.S. Department of Health & Human Services —
Background Much communicable disease control research has had little impact on local control programme policy and practice for want of an operational component. The... -
Federal
Severe reperfusion lung injury after double lung transplantation
U.S. Department of Health & Human Services —
Aim To demonstrate the effects of combined inhaled nitric oxide and surfactant replacement as treatment for acute respiratory distress syndrome. This treatment has... -
Federal
The equivalence of numbers: The social value of avoiding health decline: An experimental web-based study
U.S. Department of Health & Human Services —
Background Health economic analysis aimed at informing policy makers and supporting resource allocation decisions has to evaluate not only improvements in health but... -
Federal
Transforming growth factor-β1 blocks the enhancement of tumor necrosis factor cytotoxicity by hyaluronidase Hyal-2 in L929 fibroblasts
U.S. Department of Health & Human Services —
Background Functional antagonism between transforming growth factor beta (TGF-β) and hyaluronidase has been demonstrated. For example, testicular hyaluronidase PH-20... -
Federal
Small airway inflammation in asthma
U.S. Department of Health & Human Services —
Asthma was originally described as an inflammatory disease that predominantly involves the central airways. Pathological and physiological evidence reported during... -
Federal
Biphasic positive airway pressure ventilation (PeV+) in children
U.S. Department of Health & Human Services —
Background: Biphasic positive airway pressure (BIPAP) (also known as PeV+) is a mode of ventilation with cycling variations between two continuous positive airway... -
Federal
B cells, BAFF/zTNF4, TACI, and systemic lupus erythematosus
U.S. Department of Health & Human Services —
B cells and B-cell/T-cell collaborations are instrumental in the pathophysiology of systemic lupus erythematosus (SLE). This commentary highlights in particular the... -
Federal
Focusing on diffuse (interstitial) lung disease: a rapidly evolving field
U.S. Department of Health & Human Services —
Focusing on diffuse (interstitial) lung disease: a rapidly evolving field -
Federal
Estrogen-Astrocyte interactions: Implications for neuroprotection
U.S. Department of Health & Human Services —
Background Recent work has suggested that the ovarian steroid 17β-estradiol, at physiological concentrations, may exert protective effects in neurodegenerative... -
Federal
Need for critical care in gynaecology: a population-based analysis
U.S. Department of Health & Human Services —
Introduction The purpose of this study was to note potential gynaecological risk factors leading to intensive care and to estimate the frequency, costs and outcome of... -
Federal
Immunodepression in the surgical patient and increased susceptibility to infection
U.S. Department of Health & Human Services —
Multiple organ failure is the major problem in intensive care patients. The failure of the organ 'immune system' is frequently overlooked, however. In this issue the... -
Federal
Analysis of prolactin-modulated gene expression profiles during the Nb2 cell cycle using differential screening techniques
U.S. Department of Health & Human Services —
Background: Rat Nb2-11C lymphoma cells are dependent on prolactin for proliferation and are widely used to study prolactin signaling pathways. To investigate the role... -
Federal
Characterization of alternatively spliced products and tissue-specific isoforms of USP28 and USP25
U.S. Department of Health & Human Services —
Background The ubiquitin-dependent protein degradation pathway is essential for the proteolysis of intracellular proteins and peptides. Deubiquitinating enzymes... -
Federal
Disruption of spinal cord white matter and sciatic nerve geometry inhibits axonal growth
U.S. Department of Health & Human Services —
Background Axons within the mature mammalian central nervous system fail to regenerate following injury, usually resulting in long-lasting motor and sensory deficits.... -
Federal
Articular cartilage and changes in arthritis: Matrix degradation
U.S. Department of Health & Human Services —
While many proteases in articular cartilage have been described, current studies indicate that members of two families of metalloproteases – MMPs and the ADAMTSs –...
2,009 datasets found