2,009 datasets found
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Federal
Frailty, fitness and late-life mortality in relation to chronological and biological age
U.S. Department of Health & Human Services —
Background People age at remarkably different rates, but how to estimate trajectories of senescence is controversial. Methods In a secondary analysis of a... -
Federal
Reversible renal impairment induced by treatment with the angiotensin II receptor antagonist candesartan in a patient with bilateral renal artery stenosis
U.S. Department of Health & Human Services —
Background It is well established that ACE-inhibitors should be avoided in patients with renal artery stenosis. In recent years it has also been recommended that... -
Federal
Differential modulation of cellular death and survival pathways by conjugated bile acids
U.S. Department of Health & Human Services —
Background The liver-derived McNtcp.24 cells transport bile acids and show distinctive responses to the two classes of conjugated bile acids. Whereas taurine-... -
Federal
The burden of pediatric HIV/AIDS in Constanta, Romania: a cross-sectional study
U.S. Department of Health & Human Services —
Background By 1990, 94 percent of the acquired immunodeficiency syndrome (AIDS) cases in Romania were in children less than 13 years of age. The majority of the cases... -
Federal
Synthesis and preliminary cytotoxicity study of a cephalosporin-CC-1065 analogue prodrug
U.S. Department of Health & Human Services —
Background Antibody-directed enzyme prodrug therapy (ADEPT) is a promising new approach to deliver anticancer drugs selectively to tumor cells. In this approach, an... -
Federal
Drug interaction: Omeprazole and Phenprocoumon
U.S. Department of Health & Human Services —
Background Oral anticoagulants like the coumarin derivatives are characterised by a particularly narrow therapeutic range. Any interfering co-medication can pose a... -
Federal
Is endosonography an effective method for detection and local staging of the ampullary carcinoma? A prospective study
U.S. Department of Health & Human Services —
Background The relatively rare carcinoma of the ampulla of Vater is a neoplasia with a good prognosis compared to pancreatic cancer. Preoperative staging is important... -
Federal
Elevated calcitonin precursor levels are related to mortality in an animal model of sepsis
U.S. Department of Health & Human Services —
Background: Increased serum levels of procalcitonin (ProCT) and its component peptides have been reported in humans with sepsis. Using a hamster model of bacterial... -
Federal
β1 integrins show specific association with CD98 protein in low density membranes
U.S. Department of Health & Human Services —
Background The CD98 (4F2, FRP-1) is a widely expressed cell surface protein heterodimer composed of a glycosylated heavy chain and a non-glycosylated light chain.... -
Federal
Complete genome sequence of a novel extrachromosomal virus-like element identified in planarian
U.S. Department of Health & Human Services —
Background Freshwater planarians are widely used as models for investigation of pattern formation and studies on genetic variation in populations. Despite extensive... -
Federal
Opinion: The clinical use of selective digestive decontamination
U.S. Department of Health & Human Services —
Several recent meta-analyses have shown that the use of SDD can reduce the occurrence of nosocomial pneumonia among ventilated patients in the intensive care unit... -
Federal
In-vivo evaluation of simultaneous administration of incompatible drugs in a central venous catheter with a decreased port to port distance
U.S. Department of Health & Human Services —
Background: Multilumen catheters are commonly used in critically ill children. Their use, however, is associated with significant morbidity. We studied the... -
Federal
Expression of cytokine and chemokine mRNA and secretion of tumor necrosis factor-α by gallbladder epithelial cells: Response to bacterial lipopolysaccharides
U.S. Department of Health & Human Services —
Background In addition to immune cells, many other cell types are known to produce cytokines. Cultured normal mouse gallbladder epithelial cells, used as a model... -
Federal
Reliability, Validity and Psychometric Properties of the Greek Translation of the Center for Epidemiological Studies-Depression (CES-D) Scale
U.S. Department of Health & Human Services —
Introduction The aim of the current study was to assess the reliability, validity and psychometric properties of the Greek translation of the Center for... -
Federal
PISA. The effect of paracetamol (acetaminophen) and ibuprofen on body temperature in acute stroke: Protocol for a phase II double-blind randomised placebo-controlled trial [ISRCTN98608690]
U.S. Department of Health & Human Services —
Background During the first days after stroke, one to two fifths of the patients develop fever or subfebrile temperatures. Body temperature is a strong prognostic... -
Federal
Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases
U.S. Department of Health & Human Services —
Background The human genome contains at least 18 genes for Nudix hydrolase enzymes. Many have similar functions to one another. In order to understand their roles in... -
Federal
A p130Castyrosine phosphorylated substrate domain decoy disrupts v-Crk signaling
U.S. Department of Health & Human Services —
The adaptor protein p130Cas(Cas) has been shown to be involved in different cellular processes including cell adhesion, migration and transformation. This protein has... -
Federal
The process of genome shrinkage in the obligate symbiont
U.S. Department of Health & Human Services —
Background Very small genomes have evolved repeatedly in eubacterial lineages that have adopted obligate associations with eukaryotic hosts. Complete genome sequences... -
Federal
Meeting Report from the 20th International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium, 21-24 March 2000
U.S. Department of Health & Human Services —
Meeting Report from the 20th International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium, 21-24 March 2000 -
Federal
Modulation of L-type Ca
U.S. Department of Health & Human Services —
Background The multisubunit (α1S,α2-δ, β1a and γ1) skeletal muscle dihydropyridine receptor (DHPR) transduces membrane depolarization into release of Ca2+ from the...
2,009 datasets found