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Federal
Pleasure in decision-making situations
U.S. Department of Health & Human Services —
Background This study explores the role of pleasure in decision making. Results In Experiment 1, 12 subjects were presented with a questionnaire containing 46 items... -
Federal
Analysis of human sarcospan as a candidate gene for CFEOM1
U.S. Department of Health & Human Services —
Background Congenital fibrosis of the extraocular muscles type 1 (CFEOM1) is an autosomal dominant eye movement disorder linked to the pericentromere of chromosome 12... -
Federal
Pharmacokinetics of artesunate after single oral administration to rats
U.S. Department of Health & Human Services —
Background Artesunate is a commonly used antimalarial drug derived from artemisinin. It is rapidly converted to dihydroartemisinin. Little is known on this conversion... -
Federal
The relationship of the factor V Leiden mutation or the deletion-deletion polymorphism of the angiotensin converting enzyme to postoperative thromboembolic events following total joint arthroplasty
U.S. Department of Health & Human Services —
Background Although all patients undergoing total joint arthroplasty are subjected to similar risk factors that predispose to thromboembolism, only a subset of... -
Federal
Chromosomal aberrations in benign and malignant Bilharzia-associated bladder lesions analyzed by comparative genomic hybridization
U.S. Department of Health & Human Services —
Background Bilharzia-associated bladder cancer (BAC) is a major health problem in countries where urinary schistosomiasis is endemic. Characterization of the genetic... -
Federal
Risk factors for breast cancer in Iran: a case-control study
U.S. Department of Health & Human Services —
Background Iranian breast cancer patients are relatively younger than their Western counterparts. The objective of the present study was to investigate risk factors... -
Federal
Extracting biological information from DNA arrays: an unexpected link between arginine and methionine metabolism in
U.S. Department of Health & Human Services —
Background In global gene expression profiling experiments, variation in the expression of genes of interest can often be hidden by general noise. To determine how... -
Federal
The effect of GABA receptor ligands in experimental spina bifida occulta
U.S. Department of Health & Human Services —
Background The pathophysiology behind spina bifida and other neural tube defects (NTDs) is unclear. Folic acid is one variable, but other factors remain. Studies... -
Federal
Bacteremia in hospitalized patients with human immunodeficiency virus: A prospective, cohort study
U.S. Department of Health & Human Services —
Background Bacterial infections complicate the course of patients with human immunodeficiency virus infection. The purpose of this study was to describe the bacterial... -
Federal
Debate: Do all patients with heart failure require automatic implantable defibrillators for the prevention of sudden death?
U.S. Department of Health & Human Services —
Recent clinical trials indicate that approximately two-thirds of patients in New York Heart Association (NYHA) class II and III, who comprise almost 90% of patients... -
Federal
The role of IFN-gamma in systemic lupus erythematosus: a challenge to the Th1/Th2 paradigm in autoimmunity
U.S. Department of Health & Human Services —
Cytokines play a critical role in regulating lymphoid cell responses to most antigenic stimuli, and it is therefore very likely that these molecules profoundly affect... -
Federal
Differential response to right unilateral ECT in depressed patients: impact of comorbidity and severity of illness [ISRCTN39974945]
U.S. Department of Health & Human Services —
Background Recent electroconvulsive therapy (ECT) efficacy studies of right unilateral (RUL) ECT may not apply to real life clinics with a wide range of patients with... -
Federal
Evolution of gene fusions: horizontal transfer versus independent events
U.S. Department of Health & Human Services —
Background Gene fusions can be used as tools for functional prediction and also as evolutionary markers. Fused genes often show a scattered phyletic distribution,... -
Federal
Cre reporter strains produced by targeted insertion of
U.S. Department of Health & Human Services —
Background Several Cre reporter strains of mice have been described, in which a lacZ gene is turned on in cells expressing Cre recombinase, as well as their daughter... -
Federal
Binding of the baculovirus very late expression factor 1 (VLF-1) to different DNA structures
U.S. Department of Health & Human Services —
Background Baculovirus genomes encode a gene called very late expression factor 1 (VLF-1) that is a member of the integrase (Int) family of proteins. In this report... -
Federal
Fundamental deficiencies in the megatrial methodology
U.S. Department of Health & Human Services —
The fundamental methodological deficiency of megatrials is deliberate reduction of experimental control in order to maximize recruitment and compliance of subjects.... -
Federal
A basis for a visual language for describing, archiving and analyzing functional models of complex biological systems
U.S. Department of Health & Human Services —
Background: We propose that a computerized, internet-based graphical description language for systems biology will be essential for describing, archiving and... -
Federal
Low frequency of mutations in the core promoter and precore regions of hepatitis B virus in anti-HBe positive Brazilian carriers
U.S. Department of Health & Human Services —
Background Mutations in the core promoter and precore regions of the hepatitis B virus (HBV) genome, notably the double substitution (AGG to TGA) at nt positions... -
Federal
Preventing infection from reusable medical equipment: a systematic review
U.S. Department of Health & Human Services —
Background In 2000, the World Health Organization (WHO) had eight sets of conflicting recommendations for decontaminating medical equipment. We conducted a systematic... -
Federal
Genomic approaches to research in lung cancer
U.S. Department of Health & Human Services —
The medical research community is experiencing a marked increase in the amount of information available on genomic sequences and genes expressed by humans and other...