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Federal
Enhanced expression of genes involved in coagulation and fibrinolysis in murine arthritis
U.S. Department of Health & Human Services —
We have analyzed the pattern of procoagulant and fibrinolytic gene expression in affected joints during the course of arthritis in two murine models. In both models,... -
Federal
Heat stress is associated with decreased lactic acidemia in rat sepsis
U.S. Department of Health & Human Services —
Background: Elevated plasma lactate has been shown to correlate with mortality in patients with septic shock. Heat stress prior to sepsis has resulted in reduction in... -
Federal
Rational use of computerized protocols in the intensive care unit
U.S. Department of Health & Human Services —
Excess information in complex ICU environments exceeds human decision making limits, increasing the likelihood of clinical errors. Explicit decision-support tools... -
Federal
MCM2 - a promising marker for premalignant lesions of the lung: a cohort study
U.S. Department of Health & Human Services —
Background Because cells progressing to cancer must proliferate, marker proteins specific to proliferating cells may permit detection of premalignant lesions. Here we... -
Federal
UAG readthrough in mammalian cells: Effect of upstream and downstream stop codon contexts reveal different signals
U.S. Department of Health & Human Services —
Background Translation termination is mediated through an interaction between the release factors eRF1 and eRF3 and the stop codon within its nucleotide context.... -
Federal
The human exosome: an autoantigenic complex of exoribonucleases in myositis and scleroderma
U.S. Department of Health & Human Services —
The anti-PM/Scl autoantibodies are known to characterize a subset of autoimmune patients with myositis, scleroderma (Scl), and the PM/Scl overlap syndrome. The major... -
Federal
Production of interleukin-1 receptor antagonist by human articular chondrocytes
U.S. Department of Health & Human Services —
Interleukin-1 receptor antagonist (IL-1Ra) is a natural IL-1 inhibitor possessing anti-inflammatory properties. IL-1Ra is produced as different isoforms, one secreted... -
Federal
Hepatic glucokinase promoter polymorphism is associated with hepatic insulin resistance in Asian Indians.
U.S. Department of Health & Human Services —
Background The role of glucokinase (GCK) in the pathogenesis of maturity-onset diabetes of the young is well established. However, its role in the common form of type... -
Federal
Problems in early diagnosis of bladder cancer in a spinal cord injury patient: Report of a case of simultaneous production of granulocyte colony stimulating factor and parathyroid hormone-related protein by squamous cell carcinoma of urinary bladder
U.S. Department of Health & Human Services —
Background Typical symptoms and signs of a clinical condition may be absent in spinal cord injury (SCI) patients. Case presentation A male with paraplegia was passing... -
Federal
Recruitment curve of the soleus H-reflex in chronic back pain and lumbosacral radiculopathy
U.S. Department of Health & Human Services —
Background Needle EMG may be negative in mild or predominantly sensory lumbosacral radiculopathies. In such cases, an increase in the latency of the soleus H-reflex... -
Federal
Use of diffusion and perfusion magnetic resonance imaging as a tool in acute stroke clinical trials
U.S. Department of Health & Human Services —
In light of the slow progress in developing effective therapies for ischemic stroke, magnetic resonance imaging techniques have emerged as new tools in stroke... -
Federal
Prone positioning does not affect cannula function during extracorporeal membrane oxygenation or continuous renal replacement therapy
U.S. Department of Health & Human Services —
Introduction Prone positioning in respiratory failure has been shown to be a useful adjunct in the treatment of severe hypoxia. However, the prone position can result... -
Federal
Polymorphisms in the
U.S. Department of Health & Human Services —
Background Oxidative stress, resulting in a marked increase in the level of oxygen free radicals (OFR), has been implicated in the etiology of diabetic neuropathy... -
Federal
Mimicking microbial 'education' of the immune system: a strategy to revert the epidemic trend of atopy and allergic asthma?
U.S. Department of Health & Human Services —
Deficient microbial stimulation of the immune system, caused by hygiene, may underly the atopy and allergic asthma epidemic we are currently experiencing. Consistent... -
Federal
The relationship between the L1 and L2 domains of the insulin and epidermal growth factor receptors and leucine-rich repeat modules
U.S. Department of Health & Human Services —
Background Leucine-rich repeats are one of the more common modules found in proteins. The leucine-rich repeat consensus motif is LxxLxLxxNxLxxLxxLxxLxx- where the... -
Federal
Research Article: BMC Medical Genetics
U.S. Department of Health & Human Services —
Background Since contradictory results have been reported, we reanalysed the 77C→G transition in exon 4 of the protein-tyrosine phosphatase receptor-type C (PTPRC... -
Federal
Current practices in managing acutely disturbed patients at three hospitals in Rio de Janeiro-Brazil: a prevalence study
U.S. Department of Health & Human Services —
Background The medical management of aggressive and violent behaviour is a critical situation for which there is little evidence. In order to prepare for a randomised... -
Federal
Assessment of tissue oxygen tension: comparison of dynamic fluorescence quenching and polarographic electrode technique
U.S. Department of Health & Human Services —
Introduction and methods Dynamic fluorescence quenching is a technique that may overcome some of the limitations associated with measurement of tissue partial oxygen... -
Federal
Speciation and phylogeography in the cosmopolitan marine moon jelly,
U.S. Department of Health & Human Services —
Background The cosmopolitan moon jelly Aurelia is characterized by high degrees of morphological and ecological plasticity, and subsequently by an unclear taxonomic...