169 datasets found
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Federal
An environment with strong gravitational and magnetic field alterations synergizes to promote variations in Arabidopsis thaliana callus global transcriptional state
National Aeronautics and Space Administration —
Using diamagnetic levitation we have exposed A. thaliana in vitro callus cultures to five environments with different levels of effective gravity (from levitation... -
Federal
Biological Research in Canisters-16 (BRIC-16): Investigations of the plant cytoskeleton in microgravity with gene profiling and cytochemistry
National Aeronautics and Space Administration —
These investigations studied the fundamentals of how plants perceive gravity and develop in microgravity. It informs how gene regulation is altered by spaceflight... -
Federal
Biological Research in Canisters-16 (BRIC-16): Investigations of the plant cytoskeleton in microgravity with gene profiling and cytochemistry
National Aeronautics and Space Administration —
These investigations studied the fundamentals of how plants perceive gravity and develop in microgravity. It informs how gene regulation is altered by spaceflight... -
Federal
The influence of simulated microgravity on the proteome of Daphnia magna
National Aeronautics and Space Administration —
Background/Objectives: The waterflea Daphnia is an interesting candidate for bioregenerative life support systems (BLSS). These animals are particularly promising... -
Federal
Transcription profiling of Drosophila after exposure to microgravity in the International Space Station and in a microgravity simulator
National Aeronautics and Space Administration —
Larvae-Pupae transition flies (Drosophila) were recovered and transport for 3 days at 12-14C to arrest development until the launch site then exposed to RT (18-20C)... -
Federal
Expression data from rice calli cultured with 2,4-D
National Aeronautics and Space Administration —
Four days old rice calli were selected to grow 324h under spaceflight controls 1g-flight controls and 1g-ground controls. We used microarrays to detail the global... -
Federal
Spaceflight effects on the mouse retina: Histological gene expression and epigenetic changes after flight on STS-135
National Aeronautics and Space Administration —
We report the findings of an animal experiment onboard STS-135 investigating the molecular aspects of the impact of spaceflight on retinal biology by performing... -
Federal
Transcription profiling of Arabidopsis seedings exposed to UV-B irradiation
National Aeronautics and Space Administration —
Interaction of COP1 and UVR8 which regulate UV-B-induced photomorphogenesis and stress acclimation in Arabidopsis thaliana. -
Federal
Alteration of Proteomes in First-generation Cultures of Bacillus pumilus Spores Exposed to Outer Space
National Aeronautics and Space Administration —
Bacillus pumilus SAFR-032 was originally isolated from the Jet Propulsion Lab Spacecraft Assembly Facility and thoroughly characterized for its enhanced resistance to... -
Federal
Dynamic gene expression response to altered gravity in human myelomonocytic U937 cells [parabolic]
National Aeronautics and Space Administration —
We investigated differentially regulated genes in human myelomonocytic U937 cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to... -
Federal
The influence of simulated microgravity on the proteome of Daphnia magna
National Aeronautics and Space Administration —
Background/Objectives: The waterflea Daphnia is an interesting candidate for bioregenerative life support systems (BLSS). These animals are particularly promising... -
Federal
Identifying radiation exposure biomarkers from mouse blood transcriptome
National Aeronautics and Space Administration —
Here we present a whole-genome survey of the murine transcriptomic response to physiologically-relevant radiation doses 2 and 8 Gy. There are 18 distinct biological... -
Federal
Bystander response to 2.5 Gy of protons in a human 3-dimensional skin model in 16 h after exposure
National Aeronautics and Space Administration —
Bystander mechanisms that originate in the areas surrounding a tissue damage presumably play an important role participating in wound healing and tissue remodeling.... -
Federal
Transcription profiling of Drosophila exposed to a levitation magnet for different lengths of time
National Aeronautics and Space Administration —
Drosophila samples were exposed to the levitation magnet inside a 25mm diameter tubes with 3 ml of yeast-based Drosophila food in the bottom and a chamber of only 5... -
Federal
IMR90 4hr bystander experiment 0.5Gy alpha particle strip dish format
National Aeronautics and Space Administration —
Radiation affects tissue and cellular integrity at the level of DNA protein and metabolites of the cell and extracellular space. The effects of radiation are not... -
Federal
Microarray Analysis of Space-flown Murine Thymus Tissue
National Aeronautics and Space Administration —
Microarray Analysis of Space-flown Murine Thymus Tissue Reveals Changes in Gene Expression Regulating Stress and Glucocorticoid Receptors. We used microarrays to... -
Federal
Human skin fibroblast mitochondrial depletion 0.5 Gy alpha-particle
National Aeronautics and Space Administration —
Mitochondrial DNA-depleted human skin fibroblasts (HSF rho0) with suppressed oxidative phosphorylation were characterized by significant changes in the expression of... -
Federal
Gene expression profiling of C. elegans under various thermal conditions
National Aeronautics and Space Administration —
To realistically evaluate the effects of the environment in space it is necessary to understand the effects of external factors during sample transport from Earth to... -
Federal
Comparison of gene expression profiles of normal human bronchial epithelial cells in 2D and 3D cultural conditions
National Aeronautics and Space Administration —
The experiment is part of a project to study DNA repair process after ionizing radiation in organotypic 3-dimentional human bronchial epithlial cell culture. Human... -
Federal
Zebrafish larvae submitted to simulated microgravity on a clinostat (CLINO) at 5dpf for one day
National Aeronautics and Space Administration —
The general objective of the study was to determine modulation of gene expression by environmental factors specifically simulation of microgravity with a special...
169 datasets found