2,009 datasets found
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Federal
Gene therapy for established murine collagen-induced arthritis by local and systemic adenovirus-mediated delivery of interleukin-4
U.S. Department of Health & Human Services —
To determine whether IL-4 is therapeutic in treating established experimental arthritis, a recombinant adenovirus carrying the gene that encodes murine IL-4 (Ad-... -
Federal
Informed consent and research design in critical care medicine
U.S. Department of Health & Human Services —
Informed consent and research design in critical care medicine -
Federal
Mechanistic distinctions between agrin and laminin-1 induced aggregation of acetylcholine receptors
U.S. Department of Health & Human Services —
Background One of the earliest steps in synaptogenesis at the neuromuscular junction is the aggregation of nicotinic acetylcholine receptors at the postsynaptic... -
Federal
Beneficial effect of carboxy-PTIO on hemodynamic and blood gas changes in septic shock dogs
U.S. Department of Health & Human Services —
Background: Nitric oxide (NO) production following bacterial infection may play a physiological role in the host defense mechanism due to its antimicrobial activity.... -
Federal
The mouse anterior chamber angle and trabecular meshwork develop without cell death
U.S. Department of Health & Human Services —
Background The iridocorneal angle forms in the mammalian eye from undifferentiated mesenchyme between the root of the iris and cornea. A major component is the... -
Federal
Relatedness of baculovirus and
U.S. Department of Health & Human Services —
Background Current evidence suggests that lepidopteran baculoviruses may be divided into two phylogenetic groups based on their envelope fusion proteins. One group... -
Federal
Clinical trials in developing countries: Discussions at the '9th International Symposium on Long Term Clinical Trials', London, UK, 19-20 June 2000
U.S. Department of Health & Human Services —
This symposium provided a useful forum for the discussion of issues relating to the design and conduct of clinical trials. There is a need for greater awareness of... -
Federal
Evidence for symmetric chromosomal inversions around the replication origin in bacteria
U.S. Department of Health & Human Services —
Background: Whole-genome comparisons can provide great insight into many aspects of biology. Until recently, however, comparisons were mainly possible only between... -
Federal
Evidence that the RNAseH activity of the duck hepatitis B virus is unable to act on exogenous substrates
U.S. Department of Health & Human Services —
Background The hepadnaviral reverse transcriptase can synthesize DNA on its native RNA template within viral cores but it is usually unable to synthesize DNA... -
Federal
Using automated medical records for rapid identification of illness syndromes (syndromic surveillance): the example of lower respiratory infection
U.S. Department of Health & Human Services —
Background Gaps in disease surveillance capacity, particularly for emerging infections and bioterrorist attack, highlight a need for efficient, real time... -
Federal
Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses
U.S. Department of Health & Human Services —
Background Post-transcriptional gene silencing (PTGS) by short interfering RNA has opened up new directions in the phenotypic mutation of cellular genes. However, its... -
Federal
Mechanisms of bone loss in inflammatory arthritis: diagnosis and therapeutic implications
U.S. Department of Health & Human Services —
Rheumatoid arthritis represents an excellent model in which to gain insights into the local and systemic effects of joint inflammation on skeletal tissues. Three... -
Federal
Cloning and expression of the rabbit prostaglandin EP2 receptor
U.S. Department of Health & Human Services —
Background Prostaglandin E2 (PGE2) has multiple physiologic roles mediated by G protein coupled receptors designated E-prostanoid, or "EP" receptors. Evidence... -
Federal
Loss of cellular adhesion to matrix induces p53-independent expression of PTEN tumor suppressor
U.S. Department of Health & Human Services —
Background The tumor suppressor gene PTEN has been found mutated in many types of advanced tumors. When introduced into tumor cells that lack the wild-type allele of... -
Federal
Evaluating Niger's experience in strengthening supervision, improving availability of child survival drugs through cost recovery, and initiating training for Integrated Management of Childhood Illness (IMCI)
U.S. Department of Health & Human Services —
Background WHO and UNICEF have recently developed the "Integrated Management of Childhood Illness" (IMCI) as an efficient strategy to assist developing countries... -
Federal
Early immune development, atopy and asthma: insights from ATS 2001, May 18-23, San Francisco
U.S. Department of Health & Human Services —
There is rising evidence that the initiation of atopy and asthma may occur in early life or even during fetal life. At the American Thoracic Society meeting 2001 in... -
Federal
Aberrant meiotic behavior in
U.S. Department of Health & Human Services —
Background Agave tequilana Weber var. azul, is the only one variety permitted by federal law in México to be used for tequila production which is the most popular... -
Federal
Low molecular mass dinitrosyl nonheme-iron complexes up-regulate noradrenaline release in the rat tail artery
U.S. Department of Health & Human Services —
Background Dinitrosyl nonheme-iron complexes can appear in cells and tissues overproducing nitric oxide. It is believed that due to their chemical nature these... -
Federal
Impact factors of dermatological journals for 1991 – 2000
U.S. Department of Health & Human Services —
Background The impact factors of scientific journals are interesting but not unproblematic. It is speculated that the number of journals in which citations can be... -
Federal
Elevated serum immunoglobulin E to
U.S. Department of Health & Human Services —
Background The possible participation of diesel exhaust inhalation during the fetal period in the elevation of IgE against pollen in postnatal life was investigated....
2,009 datasets found