2,009 datasets found
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Federal
Selective alteration of gene expression in response to natural and synthetic retinoids.
U.S. Department of Health & Human Services —
Background Retinoids are very potent inducers of cellular differentiation and apoptosis, and are efficient anti-tumoral agents. Synthetic retinoids are designed to... -
Federal
Wolbachia: Evolutionary novelty in a rickettsial bacteria
U.S. Department of Health & Human Services —
Background Although closely related, the alpha-proteobacteria Wolbachia and the Rickettsiacae (Rickettsia and Ehrlichia), employ different evolutionary life history... -
Federal
Synthesis and cytotoxicity of a biotinylated CC-1065 analogue
U.S. Department of Health & Human Services —
Background The use of pretargeting technology for cancer imaging and treatment has made significant progress in the last few years. This approach takes advantage of... -
Federal
A role of proton transfer in peroxidase-catalyzed process elucidated by substrates docking calculations
U.S. Department of Health & Human Services —
Background Previous kinetic investigations of fungal-peroxidase catalyzed oxidation of N-aryl hydroxamic acids (AHAs) and N-aryl-N-hydroxy urethanes (AHUs) revealed... -
Federal
Gene discovery within the planctomycete division of the domain Bacteria using sequence tags from genomic DNA libraries
U.S. Department of Health & Human Services —
Background The planctomycetes comprise a distinct group of the domain Bacteria, forming a separate division by phylogenetic analysis. The organization of their cells... -
Federal
Is age an independent determinant of mortality in cardiac surgery as suggested by the EuroSCORE?
U.S. Department of Health & Human Services —
Background The proportion of older patients in cardiac surgery is continuously increasing. 37% of patients undergoing heart surgery in Germany in the year 2000 were... -
Federal
Deciphering the plasma membrane hallmarks of apoptotic cells: Phosphatidylserine transverse redistribution and calcium entry
U.S. Department of Health & Human Services —
Background During apoptosis, Ca2+-dependent events participate in the regulation of intracellular and morphological changes including phosphatidylserine exposure in... -
Federal
A simple method for generating full length cDNA from low abundance partial genomic clones
U.S. Department of Health & Human Services —
Background PCR amplification of target molecules involves sequence specific primers that flank the region to be amplified. While this technique is generally routine,... -
Federal
Arthritis Research: more than a journal (http://arthritis-research.com)
U.S. Department of Health & Human Services —
We are delighted to welcome you to the first printed issue ofArthritis Research, a publication that has already existed on the Internet for the last few months. This... -
Federal
IL-6 signaling by STAT3 participates in the change from hyperplasia to neoplasia in NRP-152 and NRP-154 rat prostatic epithelial cells
U.S. Department of Health & Human Services —
Background STAT3 phosphorylation is associated with the neoplastic state in many types of cancer, including prostate cancer. We investigated the role of IL-6... -
Federal
T-cell activation without proliferation in juvenile idiopathic arthritis
U.S. Department of Health & Human Services —
A study was done to determine if the differentiation and activation phenotype of T cells in synovial fluid (SF) from patients with juvenile idiopathic arthritis (JIA)... -
Federal
Debate: Albumin administration should be avoided in the critically ill
U.S. Department of Health & Human Services —
The benefit of albumin administration in the critically ill patient is unproven. Epidemiological evidence suggests that there is an increase in death among patients... -
Federal
Cytokine, activation marker, and chemokine receptor expression by individual CD4
U.S. Department of Health & Human Services —
IL-10, IL-13, IFN-γ, tumor necrosis factor (TNF)-α, LT-α, CD154, and TNF-related activation-induced cytokine (TRANCE) were expressed by 2-20% of rheumatoid arthritis... -
Federal
A simple method to assess the oxidative susceptibility of low density lipoproteins
U.S. Department of Health & Human Services —
Background Oxidative modification of low density lipoproteins (LDL) is recognized as one of the major processes involved in atherogenesis. The in vitro standardized... -
Federal
Research Article: BMC Medical Genetics
U.S. Department of Health & Human Services —
Background Narcolepsy is a common neuropsychiatric disorder characterized by increased daytime sleepiness, cataplexy and hypnagogic hallucinations. Deficiency of the... -
Federal
Isozyme and allozyme markers distinguishing two morphologically similar, medically important
U.S. Department of Health & Human Services —
Background Two common southern African mice species, Mastomys coucha and M. natalensis, are widely distributed throughout the subregion and overlap in many areas.... -
Federal
RNA triphosphatase is essential in
U.S. Department of Health & Human Services —
Background The first two steps in the capping of cellular mRNAs are catalyzed by the enzymes RNA triphosphatase and RNA guanylyltransferase. Although structural and... -
Federal
Paediatric intensive care: out of commission
U.S. Department of Health & Human Services —
Problems with commissioning paediatric intensive care stem both from difficulties in recruitment and retention of nurses, and from incoherent or nonexistent national... -
Federal
The CONSORT statement: revised recommendations for improving the quality of reports of parallel group randomized trials
U.S. Department of Health & Human Services —
To comprehend the results of a randomized controlled trial (RCT), readers must understand its design, conduct, analysis and interpretation. That goal can only be... -
Federal
The functional genomic response of developing embryonic submandibular glands to NF-kappaB inhibition
U.S. Department of Health & Human Services —
Background The proper balance between epithelial cell proliferation, quiescence, and apoptosis during development is mediated by the specific temporal and spatial...
2,009 datasets found