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Federal
The International Sepsis Forum's controversies in sepsis: corticosteroids should be used to treat septic shock
U.S. Department of Health & Human Services —
The use of corticosteroids in septic shock remains controversial. It has been demonstrated that high doses of steroids (30 mg/kg methylprednisolone) for short periods... -
Federal
Medical informatics in an undergraduate curriculum: a qualitative study
U.S. Department of Health & Human Services —
Background There is strong support for educating physicians in medical informatics, and the benefits of such education have been clearly identified. Despite this,... -
Federal
The regulation of protein synthesis and translation factors by CD3 and CD28 in human primary T lymphocytes
U.S. Department of Health & Human Services —
Background Activation of human resting T lymphocytes results in an immediate increase in protein synthesis. The increase in protein synthesis after 16–24 h has been... -
Federal
4-(N,N-dipropylamino)benzaldehyde inhibits the oxidation of
U.S. Department of Health & Human Services —
Background The signal transduction pathways mediated by retinoic acid play a critical role in the regulation of cell growth and differentiation during embryogenesis... -
Federal
Protein encapsulation in liposomes: efficiency depends on interactions between protein and phospholipid bilayer.
U.S. Department of Health & Human Services —
Background We investigated the encapsulation mechanism of enzymes into liposomes. The existing protocols to achieve high encapsulation efficiencies are basically... -
Federal
Avian papillomaviruses: the parrot
U.S. Department of Health & Human Services —
Background An avian papillomavirus genome has been cloned from a cutaneous exophytic papilloma from an African grey parrot (Psittacus erithacus). The nucleotide... -
Federal
Gene therapy moves forward - The Second International Meeting on Gene and Cell Therapies of Arthritis and Related Disorders, 17-18 May 2001, Montpellier, France
U.S. Department of Health & Human Services —
The field of gene therapy for bone and joint disorders has grown considerably over the last two and a half years. Investigators have shown that ex vivo or in vivo... -
Federal
Within the fold: assessing differential expression measures and reproducibility in microarray assays
U.S. Department of Health & Human Services —
Fold-change' cutoffs have been widely used in microarray assays to identify genes that are differentially expressed. More accurate measures are required to identify... -
Federal
Prevalence and risk factors for vaginal
U.S. Department of Health & Human Services —
Background Diabetes mellitus increases the rate of vaginal colonization and infection with Candida species Methods We surveyed women with diabetes receiving care at... -
Federal
Selecting information technology for physicians' practices: a cross-sectional study
U.S. Department of Health & Human Services —
Background Many physicians are transitioning from paper to electronic formats for billing, scheduling, medical charts, communications, etc. The primary objective of... -
Federal
Computational discovery of sense-antisense transcription in the human and mouse genomes
U.S. Department of Health & Human Services —
Overlapping but oppositely oriented transcripts have the potential to form sense-antisense perfect double-stranded (ds) RNA duplexes. A bioinformatics approach has... -
Federal
Endemic and epidemic dynamics of cholera: the role of the aquatic reservoir
U.S. Department of Health & Human Services —
Background In the last decades, attention to cholera epidemiology increased, as cholera epidemics became a worldwide health problem. Detailed investigation of V.... -
Federal
The GOLD domain, a novel protein module involved in Golgi function and secretion
U.S. Department of Health & Human Services —
Background Members of the p24 (p24/gp25L/emp24/Erp) family of proteins have been shown to be critical components of the coated vesicles that are involved in the... -
Federal
Comparative efficacy of two microdoses of a potentized homoeopathic drug, Cadmium Sulphoricum, in reducing genotoxic effects produced by cadmium chloride in mice: a time course study
U.S. Department of Health & Human Services —
Background Cadmium poisoning in the environment has assumed an alarming problem in recent years. Effective antimutagenic agents which can reverse or combat cadmium... -
Federal
Glucosinolate breakdown products as insect fumigants and their effect on carbon dioxide emission of insects
U.S. Department of Health & Human Services —
Background Glucosinolate breakdown products are volatile, therefore good candidates for insect fumigants. However, although they are insecticidal, the mode of action... -
Federal
Quality end-of-life care: A global perspective
U.S. Department of Health & Human Services —
Background Quality end-of-life care has emerged as an important concept in industrialized countries. Discussion We argue quality end-of-life care should be seen as a... -
Federal
Death, autoantigen modifications, and tolerance
U.S. Department of Health & Human Services —
Autoantibodies present in the serum of patients with a variety of inflammatory diseases have proven useful as diagnostic markers and as probes with which to elucidate... -
Federal
Variation in red cell transfusion practice in the intensive care unit: a multicentre cohort study
U.S. Department of Health & Human Services —
Objectives: To determine the degree of interinstitutional transfusion practice variation and reasons why red cells are administered in critically ill patients. Study... -
Federal
Are plant formins integral membrane proteins?
U.S. Department of Health & Human Services —
Background: The formin family of proteins has been implicated in signaling pathways of cellular morphogenesis in both animals and fungi; in the latter case, at least,... -
Federal
Endotoxemia in critically ill patients: why a reliable test could be beneficial
U.S. Department of Health & Human Services —
The detection of endotoxemia may provide a clue to the cause of sepsis or may indicate translocation of endotoxin from the gastrointestinal tract. A reliable...